Kaneda Sachi, Fujii Shinya, Fukunaga Takeru, Kakite Suguru, Kaminou Toshio, Kigawa Junzo, Harada Tasuku, Ogawa Toshihide
Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, Japan.
Abdom Imaging. 2011 Oct;36(5):612-8. doi: 10.1007/s00261-011-9719-8.
The purpose of this study was to investigate the efficacy of 3.0T MR imaging in the assessment of depth of myometrial invasion by endometrial carcinoma.
Fifty women with histopathologically confirmed endometrial carcinoma underwent preoperative MR imaging at 3.0T. MR imaging findings were compared with microscopic pathologic findings in all cases. On evaluation of MR images and histopathological findings, myometrial invasion was classified as absent (tumor confined to the endometrium), superficial (less than 50% of myometrial thickness), or deep (50% or more of myometrial thickness) by two radiologists.
The sensitivity, specificity, and accuracy of the MR imaging in distinguishing no myometrial invasion from myometrial invasion were 95/95, 60/70, and 88/90%, respectively, and no and superficial myometrial invasion from deep myometrial invasion were 88/94, 97/94, and 94/92%, respectively.
In evaluation of the depth of myometrial invasion by endometrial carcinoma, 3.0T MR imaging has a high diagnostic accuracy that is equivalent to that of previously reported 1.5T MR imaging.
本研究旨在探讨3.0T磁共振成像(MR成像)在评估子宫内膜癌肌层浸润深度方面的有效性。
50例经组织病理学确诊为子宫内膜癌的女性患者在术前接受了3.0T MR成像检查。将所有病例的MR成像结果与显微镜下病理结果进行比较。在评估MR图像和组织病理学结果时,两名放射科医生将肌层浸润分为无(肿瘤局限于子宫内膜)、浅(小于肌层厚度的50%)或深(肌层厚度的50%或更多)。
MR成像在区分无肌层浸润与肌层浸润方面的敏感性、特异性和准确性分别为95/95、60/70和88/90%,在区分无和浅肌层浸润与深肌层浸润方面分别为88/94、97/94和94/92%。
在评估子宫内膜癌肌层浸润深度时,3.0T MR成像具有较高的诊断准确性,与先前报道的1.5T MR成像相当。