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自杀企图和自杀意念患者中自杀与其他死因的预测因素:一项 30 年的前瞻性研究。

Predictors of suicide relative to other deaths in patients with suicide attempts and suicide ideation: a 30-year prospective study.

机构信息

University of Pennsylvania, United States.

出版信息

J Affect Disord. 2011 Aug;132(3):375-82. doi: 10.1016/j.jad.2011.03.006. Epub 2011 Apr 8.

Abstract

BACKGROUND

Although there is a large literature that prospectively examines predictors of suicide, low base rates of suicide and imprecision of measurement hinder definitive conclusions from being drawn.

METHOD

This study examined predictors of suicide relative to other types of death in a sample of 297 patients who had been hospitalized for suicide ideation or a suicide attempt between 1970 and 1975 and who were confirmed dead in 2005. Many predictors were measured using well-validated assessment instruments.

RESULTS

Fifty-five patients had died by suicide. Univariate predictors of an increased risk for eventual suicide included younger age, completion of at least a high school degree, a diagnosis of a psychotic disorder, taking active precautions against discovery during the attempt, and a non-zero score on the suicide item of the Beck Depression Inventory, whereas African American ethnicity was associated with a decreased risk of eventual suicide. Variables that remained significant in a multivariate analysis included younger age, African American ethnicity, and taking active precautions against discovery during the attempt. Risk factors did not vary as a function of whether eventual suicide occurred less than or more than five years after the initial evaluation or by attempter v. ideator status.

LIMITATIONS

Despite the attempt to maximize statistical power by following a high-risk sample for 30 years, the number of deaths by suicide was still relatively low.

CONCLUSIONS

Taking active precautions against discovery of a suicide attempt has the potential to be an important predictor of eventual suicide and should be assessed by clinicians. Future prospective studies should assess predictors at multiple time points to gain a richer clinical picture of the circumstances surrounding deaths by suicide.

摘要

背景

尽管有大量文献前瞻性地研究了自杀的预测因素,但自杀的低基础率和测量的不精确性阻碍了得出明确的结论。

方法

本研究在 1970 年至 1975 年间因自杀意念或自杀未遂住院的 297 名患者中,考察了自杀相对于其他类型死亡的预测因素,这些患者在 2005 年被确认为死亡。许多预测因素使用了经过充分验证的评估工具进行测量。

结果

55 名患者自杀身亡。最终自杀风险增加的单因素预测因素包括年龄较小、至少完成高中学业、精神障碍诊断、在尝试自杀时采取积极措施防止被发现,以及贝克抑郁量表自杀项目的非零得分,而非裔美国人的种族与最终自杀风险降低有关。在多变量分析中仍然显著的变量包括年龄较小、非裔美国人的种族以及在尝试自杀时采取积极措施防止被发现。风险因素的变化与最终自杀是否发生在最初评估后不到 5 年或 5 年以上、尝试自杀者与有自杀意念者的状态无关。

局限性

尽管本研究试图通过对高危样本进行 30 年的跟踪来最大限度地提高统计能力,但自杀死亡的人数仍然相对较低。

结论

采取积极措施防止发现自杀企图有可能成为最终自杀的一个重要预测因素,临床医生应该对其进行评估。未来的前瞻性研究应该在多个时间点评估预测因素,以更丰富地了解自杀死亡的情况。

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