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[三尖瓣峡部消融术后典型心房扑动患者的生活质量差异]

[Quality of life differences in patients with typical atrial flutter following cavotricuspid isthmus ablation].

作者信息

García Seara Javier, Gude Francisco, Cabanas Pilar, Martínez Sande José Luis, Fernández López Xesús, Elices Juliana, Brugada Terradellas Josep, González Juanatey José Ramón

机构信息

Unidad de Arritmias, Servicio de Cardiología, Hospital Clínico Universitario, Santiago de Compostela, A Coruña, España.

出版信息

Rev Esp Cardiol. 2011 May;64(5):401-8. doi: 10.1016/j.recesp.2010.12.014. Epub 2011 Apr 9.

Abstract

INTRODUCTION AND OBJECTIVES

The aim of the study was to assess and measure health-related quality of life (HRQoL) changes in patients with typical atrial flutter following catheter ablation. The outcome was standardized and normalized to the Spanish population adjusted by age and sex.

METHODS

Ninety-five consecutive patients who had undergone cavotricuspid isthmus ablation were included. The SF-36 questionnaire was self-administered before the procedure and at 1-year follow-up. We used the effect size and the standardized response mean as measures of responsiveness to quantify the change in HRQoL and the minimum clinically important difference to assess the smallest difference in score that patients perceived as beneficial.

RESULTS

Of the 95 patients initially included, 88 completed the 1-year follow-up. We observed a large improvement (effect size ≥0.8) on the physical functioning, role-physical , general health, and vitality scales and on the physical component summary. We detected a moderate improvement (effect size ≥0.5) on the role-emotional, social functioning, and mental health scales and on the mental component summary. On all scales except bodily pain and social activity, the improvement was clinically perceived by patients.

CONCLUSIONS

A clinically significant improvement in HRQoL measures was found in patients with typical atrial flutter who underwent cavotricuspid isthmus catheter ablation.

摘要

引言与目的

本研究旨在评估和测量典型心房扑动患者经导管消融术后与健康相关的生活质量(HRQoL)变化。结果根据年龄和性别进行标准化和归一化处理,以适用于西班牙人群。

方法

纳入95例连续接受三尖瓣峡部消融术的患者。在手术前和随访1年时,患者自行填写SF-36问卷。我们使用效应量和标准化反应均值作为反应性的测量指标,以量化HRQoL的变化,并使用最小临床重要差异来评估患者认为有益的最小得分差异。

结果

最初纳入的95例患者中,88例完成了1年的随访。我们观察到,在身体功能、角色-身体、总体健康和活力量表以及身体成分总结方面有显著改善(效应量≥0.8)。在角色-情感、社会功能和心理健康量表以及心理成分总结方面,我们检测到中度改善(效应量≥0.5)。除身体疼痛和社会活动外,所有量表上的改善在临床上均被患者感知到。

结论

接受三尖瓣峡部导管消融术的典型心房扑动患者在HRQoL测量方面有临床显著改善。

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