Department of Molecular and Human Genetics, College of Medicine, Florida International University, Miami, FL 33199, USA.
Forensic Sci Int Genet. 2012 Jan;6(1):81-90. doi: 10.1016/j.fsigen.2011.02.005. Epub 2011 Apr 8.
Based on historical records, the genetic landscape of the Bahamian archipelago is presumed to be complex and to exhibit island-specific characteristics, yet the genetic composition of the island chain, which could corroborate or refute these past accounts, remains poorly defined. As such, the current investigation was undertaken to genetically characterize 5 Bahamian populations representing the Northwest (Grand Bahama and Abaco) and Central (Eleuthera, Exuma and Long Island) Bahamas across the 15 autosomal Identifiler loci routinely employed in forensic analyses. Altogether, our findings suggest that Bahamians are a genetically heterogeneous group, with each island sampled receiving differential contributions from African, European, East Asian and Native American sources. Even though the strongest genetic signal in all 5 collections emanates from continental Africa, inter-island differentiation is noted in both the Structure and admixture analyses. The presence of alleles not in common among the 5 insular populations also signals genetic heterogeneity among the islands of the archipelago. This is especially the case when considering the Long Island population, which exhibits statistically significant genetic differences in relation to the other Bahamian collections and the New World groups of African descent (Afro-American and Afro-Caribbean) in the G-test pair-wise comparisons, even after application of the Bonferroni adjustment.
基于历史记录，巴哈马群岛的遗传格局被推测为复杂的，并表现出岛屿特异性特征，但该岛链的遗传组成，这可以证实或反驳这些过去的说法，仍然定义不清。因此，目前的调查是为了对代表巴哈马西北部（大巴哈马岛和阿巴科岛）和中部（伊柳塞拉岛、埃克苏马岛和长岛）的 5 个巴哈马人群进行遗传特征分析，使用的是法医分析中常规使用的 15 个常染色体 Identifiler 基因座。总的来说，我们的研究结果表明，巴哈马人是一个遗传上具有异质性的群体，每个被采样的岛屿都受到来自非洲、欧洲、东亚和美洲原住民的不同贡献。尽管在所有 5 个群体中最强的遗传信号都来自非洲大陆，但在结构和混合分析中都注意到了岛屿之间的分化。在 5 个岛屿群体中没有共同的等位基因也表明了群岛各岛屿之间的遗传异质性。考虑到长岛人口时尤其如此，与其他巴哈马群体和新世界非洲裔群体（非裔美国人和加勒比黑人）相比，在 G 检验的两两比较中，甚至在应用 Bonferroni 调整后，该群体在统计学上存在显著的遗传差异。
