Obstetrics & Gynecology Department, Babol University of Medical Sciences, Babol, Iran.
Taiwan J Obstet Gynecol. 2011 Mar;50(1):29-32. doi: 10.1016/j.tjog.2009.08.002.
The aim of this study was to assess uterine artery Doppler ultrasonography efficiency in prediction of adverse pregnancy outcome in high-risk pregnancies.
We selected 70 pregnant women who were high risk for development of preeclampsia, abruption, low birth weight (LBW), and preterm delivery during their pregnancy, and Doppler ultrasonography was performed for them in 18-24 gestational weeks for evaluation of uterine artery notching. Absence of diastolic flow in uterine artery waves was defined as notching. The women were divided into two groups: with notching (Group A) and without notching (Group B), then they were compared for complications such as preeclampsia, abruption, LBW, and preterm delivery.
In 70 high-risk pregnant women, 27 women (39.2%) were in Group A and the others were in Group B. The birth weight in Groups A and B was 2,897.5 ± 757.15 and 3,248.39 ± 374.27, respectively. In our study, 15 patients were delivered before 37 gestational weeks (preterm labor). Preeclampsia, abruption, and LBW were significantly higher in the group with positive notching, but preterm delivery did not show any statistical difference between the two groups.
According to the results, uterine artery Doppler ultrasonography had high negative predictive value for prediction of preeclampsia, abruption, and LBW. Therefore, absence of uterine artery notching in mid-trimester evaluation of high-risk pregnant women may predict better pregnancy outcome. We recommend Doppler ultrasonography for all high-risk pregnant women in second trimester for prediction of pregnancy outcome.
本研究旨在评估子宫动脉多普勒超声在预测高危妊娠不良妊娠结局中的效率。
我们选择了 70 名高危孕妇，这些孕妇在妊娠期间有发生子痫前期、胎盘早剥、低出生体重（LBW）和早产的风险，在 18-24 孕周对她们进行子宫动脉多普勒超声检查以评估子宫动脉切迹。子宫动脉波中无舒张期血流被定义为切迹。将这些孕妇分为两组：有切迹（A 组）和无切迹（B 组），然后比较两组的并发症，如子痫前期、胎盘早剥、LBW 和早产。
在 70 名高危孕妇中，27 名（39.2%）孕妇在 A 组，其余在 B 组。A 组和 B 组的出生体重分别为 2897.5±757.15 和 3248.39±374.27。在我们的研究中，有 15 名患者在 37 孕周前分娩（早产）。在有阳性切迹的组中，子痫前期、胎盘早剥和 LBW 的发生率明显更高，但早产在两组之间没有统计学差异。
根据结果，子宫动脉多普勒超声对预测子痫前期、胎盘早剥和 LBW 具有很高的阴性预测值。因此，在中孕期对高危孕妇进行子宫动脉多普勒超声检查时，如果没有发现切迹，可能预示着更好的妊娠结局。我们建议对所有高危孕妇在孕中期进行多普勒超声检查，以预测妊娠结局。
