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脐带华通胶含量与出生体重呈正相关。

Positive correlation between the quantity of Wharton's jelly in the umbilical cord and birth weight.

机构信息

Delivery Unit, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey.

出版信息

Taiwan J Obstet Gynecol. 2011 Mar;50(1):33-6. doi: 10.1016/j.tjog.2009.11.002.

Abstract

OBJECTIVE

To determine the possible protective effects of Wharton's jelly (WJ) in umbilical cord and fetal growth by investigating the relationship between the amount of WJ and fetal birth weight.

MATERIALS AND METHODS

This study enrolled 299 women who delivered after an uneventful pregnancy. After separation of the placenta, a 5cm long section of umbilical cord was removed by scalpel. The weight of the cord section; the weight, volume, and density of its WJ; and the weight of the newborn and placenta were measured.

RESULTS

A significant positive correlation was found between WJ quantity, birth weight (p=0.002), and placental weight (p=0.003), whereas a significant negative correlation was observed for WJ density, fetal growth (p=0.035), and placental growth (p=0.002). WJ density was 1.63 ± 0.27g/mL. No significant correlation was found between the amount of WJ and weight gained during pregnancy (p=0.274) or maternal age (p=0.220).

CONCLUSION

As the amount of WJ increases, fetal weight increases. Accordingly, the amount of WJ might be a factor that influences fetal growth.

摘要

目的

通过研究脐带华通氏胶(Wharton's jelly,WJ)含量与胎儿出生体重之间的关系,确定脐带 WJ 对胎儿生长的可能保护作用。

材料与方法

本研究纳入了 299 名经无并发症妊娠分娩的女性。用手术刀分离胎盘后,切取 5cm 长的一段脐带。测量脐带段的重量、WJ 的重量、体积和密度,以及新生儿和胎盘的重量。

结果

WJ 含量与出生体重(p=0.002)和胎盘重量(p=0.003)呈显著正相关,而与 WJ 密度、胎儿生长(p=0.035)和胎盘生长(p=0.002)呈显著负相关。WJ 密度为 1.63±0.27g/mL。WJ 含量与孕期体重增加(p=0.274)或产妇年龄(p=0.220)无显著相关性。

结论

随着 WJ 含量的增加,胎儿体重增加。因此,WJ 含量可能是影响胎儿生长的一个因素。

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