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老年人自杀流行病学转变假说的进一步证据。

Further evidence for epidemiological transition hypothesis for elderly suicides.

作者信息

Shah Ajit

机构信息

International School for Communities, Rights and Inclusion, University of Central Lancashire, Preston, United Kingdom.

出版信息

J Inj Violence Res. 2011 Jan;3(1):29-34. doi: 10.5249/jivr.v3i1.71.

Abstract

BACKGROUND

A developmental model of epidemiological transition for elderly suicide rates with four sequential stages has been developed to simultaneously explain cross-national variations in elderly suicide rates, trends over time for elderly suicide rates and age-associated trends in suicides rates reported in the literature. This model was supported by demonstration of a curvilinear (inverted U-shaped curve) relationship between elderly suicide rates and socio-economic status fitting the quadratic equation Y = A + BX - CX2 (where Y is the suicide rate, X is the socio-economic status and A,B, and C are constants) in both sexes. However, this relationship was derived from a cross-sectional study and, therefore, only an association can be inferred. One way to substantiate this further would be to examine the above curvilinear relationship between suicide rates and socio-economic status in a series of younger age-bands because a large part of the epidemiological transition hypothesis was contingent upon the impact of socio-economic status, through a series of mechanisms, on life expectancy. It was hypothesized that the curvilinear (inverted U-shaped curve) relationship between suicide rates and socio-economic status would be absent in younger age-bands and may be present in the younger age-bands closer to the older age-bands (i.e. 45-54 years and 55-64 years).

METHODS

The curvilinear relationship between suicide rates in five age-bands 15-24 years to 55-64 years in both sexes and gross national domestic product (GDP), a measure of socio-economic status, fitting the above quadratic equation was examined with curve estimation regression model using data from the World Health Organization.

RESULTS

In males in the age-bands 35-44 years, 45-54 years and 55-64 years there was a statistically significant curvilinear (inverted U-shaped curve) relationship with GDP and fitted the quadratic equation Y = A + BX - CX2; this relationship was absent in males in the age-bands 15-24 years and 25-34 years. In females in the age-bands 45-54 years and 55-64 years there was a statistically significant curvilinear with GDP (inverted U-shaped curve) and fitted the quadratic equation Y = A + BX - CX2; this relationship was absent in females in the age-bands 15-24 years, 25-34 years and 35-44 years.

CONCLUSIONS

Although caution should be exercised in accepting the model of the epidemiological transition hypothesis for elderly suicide rates because it had been generated from cross-sectional data using an ecological design, the findings of the current study of suicide rates in younger age-bands provide support for this hypothesis. ‎

摘要

背景

已建立一个老年自杀率的流行病学转变发展模型,该模型有四个连续阶段,旨在同时解释老年自杀率的跨国差异、老年自杀率随时间的变化趋势以及文献中报道的自杀率的年龄相关趋势。该模型得到了两性老年自杀率与社会经济地位之间曲线关系(倒U形曲线)的支持,该关系符合二次方程Y = A + BX - CX²(其中Y为自杀率,X为社会经济地位,A、B和C为常数)。然而,这种关系来自横断面研究,因此只能推断出一种关联。进一步证实这一点的一种方法是在一系列较年轻的年龄组中研究自杀率与社会经济地位之间的上述曲线关系,因为流行病学转变假说的很大一部分取决于社会经济地位通过一系列机制对预期寿命的影响。据推测,自杀率与社会经济地位之间的曲线关系(倒U形曲线)在较年轻的年龄组中不存在,而可能在更接近老年年龄组(即45 - 54岁和55 - 64岁)的较年轻年龄组中存在。

方法

使用世界卫生组织的数据,通过曲线估计回归模型研究了15 - 24岁至55 - 64岁五个年龄组中两性自杀率与国民生产总值(GDP,社会经济地位的一种衡量指标)之间符合上述二次方程的曲线关系。

结果

在35 - 44岁、45 - 54岁和55 - 64岁年龄组的男性中,与GDP存在统计学上显著的曲线关系(倒U形曲线),符合二次方程Y = A + BX - CX²;在15 - 24岁和25 - 34岁年龄组的男性中不存在这种关系。在45 - 54岁和55 - 64岁年龄组的女性中,与GDP存在统计学上显著的曲线关系(倒U形曲线),符合二次方程Y = A + BX - CX²;在15 - 24岁、25 - 34岁和35 - 44岁年龄组的女性中不存在这种关系。

结论

尽管在接受老年自杀率的流行病学转变假说模型时应谨慎,因为它是使用生态设计从横断面数据得出的,但当前对较年轻年龄组自杀率的研究结果为这一假说提供了支持。

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