尼日利亚西南部农村地区的破伤风：一项十年回顾性研究。
Tetanus in a rural setting of South-Western Nigeria: a ten-year retrospective study.
机构信息
Department of Internal Medicine.
出版信息
Libyan J Med. 2009 Jun 1;4(2):78-80. doi: 10.4176/081125.
We review the records of 79 tetanus patients in two hospitals (one tertiary and one secondary level) in Owo, Ondo state, Nigeria from 1997 to 2006. The male: female ratio was 3:1. Ages were 14-70 years (mean 33.25 years, SD ±16.76). The overall case fatality rate (CFR), 32.91%, did was not significantly different in the two hospitals. CFR for men was 32.10% and for women 35.29%. The main factor indicative of bad prognosis was a short hospitalization period. It was observed that 30.38% of our patients were discharged against medical advice (DAMA), that financial constraint was the underlying problem in 50% of cases, and that the trend of DAMA occurred at the two study sites. This DAMA phenomenon could pose a great danger to the eradication of this vaccine preventable disease in rural areas.
我们回顾了 1997 年至 2006 年尼日利亚奥沃州两家医院（一家为三级医院，一家为二级医院）的 79 例破伤风患者的记录。男女比例为 3:1。年龄为 14-70 岁（平均 33.25 岁，标准差±16.76）。两家医院的总体病死率（CFR）为 32.91%，无显著差异。男性的病死率为 32.10%，女性为 35.29%。预示预后不良的主要因素是住院时间短。我们观察到，30.38%的患者未经医嘱出院（DAMA），50%的病例存在经济困难问题，并且在两个研究地点都存在 DAMA 现象。这种 DAMA 现象可能对农村地区消除这种疫苗可预防疾病构成巨大威胁。
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