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激光散斑对比分析中空间平均的校正。

Correction for spatial averaging in laser speckle contrast analysis.

作者信息

Thompson Oliver, Andrews Michael, Hirst Evan

出版信息

Biomed Opt Express. 2011 Mar 30;2(4):1021-9. doi: 10.1364/BOE.2.001021.

DOI:10.1364/BOE.2.001021
PMID:21483623
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3072115/
Abstract

Practical laser speckle contrast analysis systems face a problem of spatial averaging of speckles, due to the pixel size in the cameras used. Existing practice is to use a system factor in speckle contrast analysis to account for spatial averaging. The linearity of the system factor correction has not previously been confirmed. The problem of spatial averaging is illustrated using computer simulation of time-integrated dynamic speckle, and the linearity of the correction confirmed using both computer simulation and experimental results. The valid linear correction allows various useful compromises in the system design.

摘要

由于所使用相机中的像素大小,实际的激光散斑对比度分析系统面临散斑空间平均化的问题。现有的做法是在散斑对比度分析中使用一个系统因子来考虑空间平均化。此前尚未证实系统因子校正的线性。通过时间积分动态散斑的计算机模拟来说明空间平均化问题,并通过计算机模拟和实验结果来证实校正的线性。有效的线性校正允许在系统设计中进行各种有用的折衷。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/c895e5da8677/boe-2-4-1021-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/95a80384f8dc/boe-2-4-1021-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/3db64001d0dd/boe-2-4-1021-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/357a80e7d843/boe-2-4-1021-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/ab02a9750e69/boe-2-4-1021-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/d691cd9a0a4f/boe-2-4-1021-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/365b4eb830be/boe-2-4-1021-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/c895e5da8677/boe-2-4-1021-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/95a80384f8dc/boe-2-4-1021-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/3db64001d0dd/boe-2-4-1021-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/357a80e7d843/boe-2-4-1021-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/ab02a9750e69/boe-2-4-1021-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/d691cd9a0a4f/boe-2-4-1021-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/365b4eb830be/boe-2-4-1021-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/3072115/c895e5da8677/boe-2-4-1021-g007.jpg

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Tissue perfusion measurements: multiple-exposure laser speckle analysis generates laser Doppler-like spectra.
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Choice of numerical implementation of spatial contrast calculation impacts microcirculation quantitation in laser speckle contrast imaging.空间对比度计算的数值实现方式的选择会影响激光散斑对比成像中的微循环定量。
J Biomed Opt. 2025 Apr;30(4):046006. doi: 10.1117/1.JBO.30.4.046006. Epub 2025 Apr 16.
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