Department of Orthopaedics, Thomas Jefferson University, Philadelphia, USA.
Eur Spine J. 2011 Aug;20(8):1323-30. doi: 10.1007/s00586-011-1782-x. Epub 2011 Apr 13.
This is a retrospective case series to evaluate clinical variables, complications and outcome of 50 patients who underwent anterior lumbar interbody fusion (ALIF) supplemented with posterior percutaneous pedicle screw fixation for degenerative conditions of the lumbar spine. Twenty-four patients underwent single-level fusion and 26 patients had a two-level fusion for a total of 76 levels fused. The mean lengths of the anterior and posterior (including repositioning) portions of the procedure were 131 and 102 min, respectively. The mean estimated blood loss for the entire procedure was 288 ml. The overall adverse event rate was 12%. The mean VAS score for leg pain, VAS score for back pain and mean ODI all improved postoperatively. This study found that ALIF using allograft bone and rhBMP-2 combined with percutaneous pedicle screw fixation had a high fusion rate and a low incidence of perioperative complications. Patient outcomes showed significant improvements in back and leg pain and physical functioning.
这是一项回顾性病例系列研究，评估了 50 例因腰椎退行性疾病行前路腰椎体间融合（ALIF）联合后路经皮椎弓根螺钉固定的患者的临床变量、并发症和结果。24 例患者行单节段融合，26 例患者行两节段融合，共融合 76 个节段。前路和后路（包括复位）的平均手术时间分别为 131 分钟和 102 分钟。整个手术过程的平均估计失血量为 288 毫升。总的不良事件发生率为 12%。术后腿痛的平均视觉模拟评分（VAS）、腰痛的 VAS 评分和 ODI 均值均有改善。本研究发现，同种异体骨和 rhBMP-2 联合经皮椎弓根螺钉固定的 ALIF 具有较高的融合率和较低的围手术期并发症发生率。患者的预后显示，腰背疼痛和身体功能均有显著改善。
