Department of Radiological Sciences, University of Messina, Policlinico "G. Martino," Messina, Italy.
Inflamm Bowel Dis. 2011 May;17(5):1209-22. doi: 10.1002/ibd.21548. Epub 2010 Nov 5.
Considering that multiple imaging examinations are often necessary for monitoring Crohn's disease (CD) activity and severity in order to guide and monitor appropriate treatment, the ideal imaging test would be reproducible, well tolerated by patients, and free of ionizing radiation. For these reasons recent studies have highlighted the role of a magnetic resonance imaging (MRI) technique optimized for small bowel imaging in the evaluation of small bowel disorders. In this regard there are two main methodological approaches represented by MR enterography, following administration of an oral contrast medium, and MR enteroclysis, following administration of contrast medium through a nasojejuneal tube. MRI may be used to demonstrate the pathologic findings and complications of CD. In particular, MR has excellent sensitivity and specificity, ranging from 88%-98% and 78%-100%, respectively, for the detection of active inflammation, wall thickening, ulcerations, increased wall enhancement, increased vascularity, perienteric inflammation, and reactive adenopathy. MR also allows more accurate identification of associated complications including penetrating and fibrostenotic disease as well as the more rare extraintestinal manifestations that are usually associated with severe and longstanding intestinal inflammation, the latter often guiding the therapeutic approach. In the progression of CD some rare complications can occur that, to our knowledge, were only briefly or never mentioned in the radiological literature regarding MR enterography or enteroclysis and in which the application of these techniques play a key role.
鉴于为了指导和监测适当的治疗,经常需要对克罗恩病 (CD) 的活动和严重程度进行多次影像学检查,因此理想的影像学检查应该是可重复的、患者耐受良好且无电离辐射的。出于这些原因,最近的研究强调了针对小肠成像进行优化的磁共振成像 (MRI) 技术在评估小肠疾病中的作用。在这方面,有两种主要的方法学方法,一种是口服造影剂后进行的磁共振肠造影术,另一种是经鼻胃空肠管给予造影剂后进行的磁共振肠灌洗术。MRI 可用于显示 CD 的病理发现和并发症。特别是,MR 对活动性炎症、壁增厚、溃疡、壁增强增加、血管增多、肠周炎症和反应性淋巴结肿大的检测具有出色的敏感性和特异性,分别为 88%-98%和 78%-100%。MR 还可以更准确地识别相关并发症,包括穿透性和纤维狭窄性疾病以及更罕见的肠外表现,这些表现通常与严重和长期的肠道炎症相关,后者通常指导治疗方法。在 CD 的进展过程中,可能会出现一些罕见的并发症,据我们所知,这些并发症在关于磁共振肠造影术或肠灌洗术的放射学文献中仅被简要提及或从未提及,而这些技术的应用在其中发挥了关键作用。