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1例过敏性紫癜性肾炎缓解3年后复发。

A case of Henoch-Schoenlein purpura nephritis recurring after 3 years remission.

作者信息

Ushijima Yumiko, Kawasaki Yukihiko, Kaneko Mariko, Haneda Kentaro, Sakai Nobuko, Suyama Kazuhide, Hashimoto Koichi, Hosoya Mitsuaki

机构信息

Department of Pediatrics, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, Japan.

出版信息

Fukushima J Med Sci. 2010 Jun;56(1):50-6. doi: 10.5387/fms.56.50.

Abstract

Henoch-Schoenlein purpura (HSP) is a systemic disorder characterized by leukocytoclastic vasculitis involving the capillaries with IgA immune complexes deposition, and about 7% of patients with HSP experience recurrence. Most patients with recurring of HSP nephritis show a recurrence of clinical symptoms over a period ranging from 2 to 5 months, even after the disappearance of initial symptoms. Here we report a 9-year-old girl diagnosed with recurrent HSP and severe crescentic glomerulonephritis 3 years after complete resolution of the initial symptoms of HSP. Our case is unique in respect of the recurrence at more than 3 years after the complete resolution of initial symptoms, suggesting that careful followup is required in spite of improved renal symptoms in cases of HSP.

摘要

过敏性紫癜(HSP)是一种系统性疾病,其特征为白细胞破碎性血管炎,累及毛细血管并有IgA免疫复合物沉积,约7%的HSP患者会复发。大多数HSP肾炎复发患者在初始症状消失后,会在2至5个月的时间内出现临床症状复发。在此,我们报告一名9岁女孩,在HSP初始症状完全缓解3年后被诊断为复发性HSP和严重新月体性肾小球肾炎。我们的病例在初始症状完全缓解3年多后复发,这一点很独特,提示对于HSP病例,尽管肾脏症状有所改善,但仍需仔细随访。

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