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金(Au)纳米粒子:基于三脚膦配体稳定的尺寸和形态控制及其抗菌活性。

Au(degrees)-nanoparticles: control size and morphology stabilized by tripodal phosphine based ligands and their antimicrobial activity.

机构信息

Materials Science Division, North East Institute of Science and Technology (CSIR), Jorhat 785006, India.

出版信息

J Biomed Nanotechnol. 2011 Feb;7(1):152-3. doi: 10.1166/jbn.2011.1245.

DOI:10.1166/jbn.2011.1245
PMID:21485847
Abstract

Metal nanoparticles have attracted great attention due to their potential applications in the fields like electronics, opto-electronics, bioscience, catalysis, etc. New ligands 1,1,1-tris (diphenylphosphinomethyl) ethane [CH3C(CH2PPh2)3] 1 and 1,1,1-tris-(diphenylphosphino methyl) ethane trisulphide [CH3C(CH2P(S)Ph2)3] 2 for stabilization of Au(degrees)-nanoparticles having small core diameter were prepared. The Au(degrees)-nanoparticles are more active against Gram(+) bacteria, e.g., Staphylococcus aureus than Gram(-) bacteria. Among the two Au(degrees)-nanoparticles, the ligand 1 stabilized particles shows higher activity.

摘要

金属纳米粒子由于其在电子学、光电学、生物科学、催化等领域的潜在应用而引起了极大的关注。新的配体 1,1,1-三(二苯膦甲基)乙烷 [CH3C(CH2PPh2)3] 1 和 1,1,1-三(二苯膦甲基)乙烷三硫化物 [CH3C(CH2P(S)Ph2)3] 2 被制备用于稳定具有小核心直径的金(°)纳米粒子。金(°)纳米粒子对革兰氏阳性菌(例如金黄色葡萄球菌)比革兰氏阴性菌更具活性。在这两种金(°)纳米粒子中,配体 1 稳定的颗粒显示出更高的活性。

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