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吸烟与慢性疼痛:一种真实却令人困惑的关系。

Smoking and chronic pain: a real-but-puzzling relationship.

作者信息

Weingarten Toby N, Shi Yu, Mantilla Carlos B, Hooten W Michael, Warner David O

机构信息

Mayo Clinic, USA.

出版信息

Minn Med. 2011 Mar;94(3):35-7.

PMID:21485923
Abstract

Smoking produces profound changes in physiology beyond those associated with the delivery of nicotine to the bloodstream. It has long been known that these changes put patients at risk for heart disease, cancers, and lung diseases. More recently, it has been discovered that smoking is a risk factor for chronic pain. Robust epidemiological evidence is showing that smokers not only have higher rates of chronic pain but also rate their pain as more intense than nonsmokers. Because the relationship between smoking and pain is of relevance to clinicians in many specialties, researchers at Mayo Clinic are examining this relationship in depth. This article describes some of what they and others have discovered in recent years about the interactions between smoking and chronic pain.

摘要

吸烟对生理产生的深远影响,远不止于尼古丁进入血液所带来的那些影响。长期以来,人们都知道这些变化会使患者面临患心脏病、癌症和肺部疾病的风险。最近,人们发现吸烟是慢性疼痛的一个风险因素。有力的流行病学证据表明,吸烟者不仅慢性疼痛的发生率更高,而且他们对疼痛的评分也比不吸烟者更高。由于吸烟与疼痛之间的关系与许多专科的临床医生都有关系,梅奥诊所的研究人员正在深入研究这种关系。本文介绍了他们以及其他研究人员近年来在吸烟与慢性疼痛之间的相互作用方面所发现的一些情况。

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1
Smoking and chronic pain: a real-but-puzzling relationship.吸烟与慢性疼痛:一种真实却令人困惑的关系。
Minn Med. 2011 Mar;94(3):35-7.
2
The smoking gun: many conditions associated with tobacco exposure may be attributable to paradoxical compensatory autonomic responses to nicotine.确凿证据:许多与烟草暴露相关的病症可能归因于对尼古丁的反常代偿性自主反应。
Med Hypotheses. 2005;64(6):1073-9. doi: 10.1016/j.mehy.2004.11.040.
3
Smoking and pain: pathophysiology and clinical implications.吸烟与疼痛:病理生理学与临床意义。
Anesthesiology. 2010 Oct;113(4):977-92. doi: 10.1097/ALN.0b013e3181ebdaf9.
4
[Obstacles to stopping smoking among patients with vascular risk].[血管风险患者戒烟的障碍]
J Mal Vasc. 1997 Mar;22(1):56-61.
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Platelet monoamine oxidase, smoking cessation, and tobacco withdrawal symptoms.血小板单胺氧化酶、戒烟与烟草戒断症状
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6
Zyban: a new aid to smoking cessation treatment--will it work for psychiatric patients?畅沛:戒烟治疗的新辅助手段——对精神科患者有效吗?
J Psychosoc Nurs Ment Health Serv. 1999 Feb;37(2):36-42; quiz 43-4.
7
Nicotine dependence, withdrawal symptoms, and adolescents' readiness to quit smoking.尼古丁依赖、戒断症状与青少年戒烟意愿
Nicotine Tob Res. 2001 May;3(2):151-5. doi: 10.1080/14622200110043068.
8
Oxygen as a therapy for reducing nicotine withdrawal symptoms.氧气作为减轻尼古丁戒断症状的一种疗法。
Med Hypotheses. 2005;65(6):1161-4. doi: 10.1016/j.mehy.2005.05.021. Epub 2005 Jul 5.
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[Nicotine replacement therapy and smoking cessation: what choice for its status?].[尼古丁替代疗法与戒烟:其地位该如何选择?]
Bull Acad Natl Med. 1999;183(6):1175-82; discussion 1182-7.
10
Bupropion for the treatment of nicotine withdrawal and craving.安非他酮用于治疗尼古丁戒断和成瘾。
Expert Rev Neurother. 2006 Jul;6(7):965-81. doi: 10.1586/14737175.6.7.965.

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Braz J Med Biol Res. 2014 Sep;47(9):818-25. doi: 10.1590/1414-431x20143710. Epub 2014 Jul 25.
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An Association between Emotional Responsiveness and Smoking Behavior.情绪反应与吸烟行为之间的关联。
J Addict. 2013;2013:276024. doi: 10.1155/2013/276024. Epub 2012 Dec 13.