Department of Chemistry, Brown University, 324 Brook Street, Providence, Rhode Island 02912, USA.
J Am Chem Soc. 2011 May 4;133(17):6596-602. doi: 10.1021/ja109041z. Epub 2011 Apr 12.
The dimeric structure is characterized for a chiral amide base complex consisting of an (S)-N-isopropyl-O-triisopropylsilyl valinol ligand and lithium. The complex is characterized by a variety of NMR techniques, including multinuclear one- and two-dimensional NMR experiments and diffusion-ordered NMR spectroscopy (DOSY) as well as diffusion coefficient-formula weight (D-fw) correlation analyses. Spartan calculations are presented which support the structural assignment. This structural characterization leads to an explanation of the behavior and the reactivity of these complexes in solution.
二聚结构的特点是含有（S）-N-异丙基-O-三异丙基硅基缬氨醇配体和锂的手性酰胺碱配合物。该配合物的特点是通过各种 NMR 技术进行了表征，包括多核一维和二维 NMR 实验以及扩散有序 NMR 光谱（DOSY）以及扩散系数-分子量（D-fw）相关分析。提供了 Spartan 计算结果，这些结果支持了结构的归属。这种结构表征导致了对这些配合物在溶液中的行为和反应性的解释。
