Department of Periodontology, Center for Dental, Oral, and Maxillofacial Medicine (Carolinum), Johann Wolfgang Goethe-University Frankfurt am Main, Frankfurt am Main, Germany.
J Periodontol. 2011 Nov;82(11):1536-47. doi: 10.1902/jop.2011.100615. Epub 2011 Apr 12.
This case report describes the clinical and microbiologic long-term outcome 5 years after periodontal therapy of two siblings diagnosed with Papillon-Lefèvre syndrome (PLS) and tinea capitis.
In 2005, two brothers diagnosed with PLS and tinea capitis began periodontal treatment. Both of them showed premature mobility of the primary dentition, markedly increased probing depths, and subgingival Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans; Aa). Initial therapy consisted of scaling and root planing based on the concept of full-mouth disinfection, extraction of periodontally hopeless deciduous teeth, and systemic antibiotics. Reevaluation of clinical parameters revealed a dramatic improvement. After that, the patients were enrolled in a stringent maintenance program. Microbiologic monitoring was performed 1 and 5 years after treatment.
Five years after initial treatment, the periodontal situation was stable in both patients. Residual deciduous teeth, with the exception of one tooth, could be retained and no further teeth were lost. Further disease progression on the previously involved teeth was controlled, and development of periodontitis on erupting teeth was prevented for a period of 5 years.
Even periodontally affected deciduous teeth can be treated successfully in patients with PLS. Suppression of Aa and a stringent maintenance program are of high importance.
本病例报告描述了两例患有掌跖角化-牙周病综合征（PLS）和头癣的兄弟姐妹在牙周治疗 5 年后的临床和微生物学长期疗效。
2005 年，两名被诊断为 PLS 和头癣的兄弟开始接受牙周治疗。他们都表现出乳牙过早松动、探诊深度显著增加以及龈下伴放线聚集杆菌（以前称为放线杆菌 actinomycetemcomitans；Aa）。初始治疗包括基于全口消毒概念的刮治和根面平整、牙周丧失乳牙的拔除以及全身抗生素治疗。临床参数的重新评估显示出显著改善。此后，患者被纳入严格的维护计划。在治疗后 1 年和 5 年进行微生物监测。
在初始治疗后 5 年，两名患者的牙周状况均稳定。除了一颗牙齿外，其余的乳牙都可以保留，没有进一步的牙齿脱落。先前受累牙齿的进一步疾病进展得到控制，并且在 5 年内预防了萌出牙齿的牙周炎发展。
即使是患有 PLS 的患者，牙周受累的乳牙也可以成功治疗。抑制 Aa 和严格的维护计划非常重要。
