[Effect of sustained release alprenolol in hypertension uncontrolled by chlorothiazide and dihydralazine. Study in double blind (author's transl)].

In 20 hypertensive patients with functioning renal graft, sustained release alprenolol or placebo was given orally for 2 months, in combination with chlorothiazide and dihydralazine, after previous failure of these 2 last drugs. Blood pressure was normalized with alprenolol during the length of the study, but is was not with placebo. Mean plasma renine level decreased of 45 p. cent.