特发性肠系膜炎性静脉闭塞病所致急性暴发性结肠炎。
Acute fulminant colitis caused by idiopathic mesenteric inflammatory veno-occlusive disease.
作者信息
Canavan James B, Coss Alan, Leader Mary, Patchett Stephen E
机构信息
Department of Gastroenterology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin, Republic of Ireland.
出版信息
Case Rep Gastroenterol. 2007 Dec 13;1(1):152-6. doi: 10.1159/000112222.
Mesenteric inflammatory veno-occlusive disease (MIVOD) is an uncommon but important cause of bowel inflammation. MIVOD is characterised by lymphocytic inflammation and non-thrombotic occlusion of the mesenteric venules and veins. We present the case of a young man who presented with acute fulminant colitis, requiring colectomy. The differential diagnosis, pathogenesis and treatment are discussed. This case illustrates the rapid progression from 'well' to 'colectomy' that can occur with MIVOD. MIVOD should be considered in the differential diagnosis of colitis that does not respond to conventional medical treatment.
肠系膜炎性静脉闭塞性疾病（MIVOD）是一种罕见但重要的肠道炎症病因。MIVOD的特征是淋巴细胞性炎症以及肠系膜小静脉和静脉的非血栓性闭塞。我们报告了一名患有急性暴发性结肠炎并需要进行结肠切除术的年轻男性病例。文中讨论了鉴别诊断、发病机制和治疗方法。该病例说明了MIVOD可出现从“病情良好”到“需行结肠切除术”的快速进展过程。对于对传统药物治疗无反应的结肠炎，鉴别诊断时应考虑MIVOD。
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