胎儿异常右锁骨下动脉的相关异常和结局。
Associated anomalies and outcome of fetal aberrant right subclavian artery.
机构信息
Department of Obstetrics and Gynecology, Bakirkoy Women's and Children's Teaching and Research Hospital, Bakirkoy, Istanbul, Turkey.
出版信息
Arch Gynecol Obstet. 2012 Jan;285(1):27-30. doi: 10.1007/s00404-011-1907-9. Epub 2011 Apr 13.
PURPOSE
To determine the frequency of aberrant right subclavian artery among the low-risk fetuses and to evaluate its association with chromosomal abnormalities and the other congenital heart diseases.
METHODS
A total of 4,125 consecutive fetuses were examined for the presence of aberrant right subclavian artery that arises from the descending aorta distal to the left subclavian artery.
RESULTS
Aberrant right subclavian artery was detected in 17 cases (0.4%). In nine cases it was an isolated finding. In four cases (23.5%) it was accompanied by another cardiac defect. Extracardiac malformations were present in three fetuses (17.6%). Among the 13 cases of aberrant right subclavian artery in which the karyotypes were known, one case presented with Down syndrome (7.6%). In this fetus, aberrant right subclavian artery was the only finding.
CONCLUSION
These findings suggest that aberrant right subclavian may be an isolated finding in trisomy 21. The visualization of subclavian artery should be a part of fetal echocardiographic examination as it may be a valuable marker for Down syndrome.
目的
确定低危胎儿中异常右锁骨下动脉的发生频率，并评估其与染色体异常和其他先天性心脏病的关系。
方法
对 4125 例连续胎儿进行检查，以确定异常右锁骨下动脉是否从左锁骨下动脉远端的降主动脉发出。
结果
在 17 例（0.4%）中检测到异常右锁骨下动脉。其中 9 例为孤立性发现。在 4 例（23.5%）中，它伴有另一种心脏缺陷。在 3 例（17.6%）胎儿中存在心脏外畸形。在已知 13 例异常右锁骨下动脉的病例中，1 例患有唐氏综合征（7.6%）。在这例胎儿中，异常右锁骨下动脉是唯一的发现。
结论
这些发现表明，异常右锁骨下动脉可能是 21 三体的孤立性发现。锁骨下动脉的可视化应作为胎儿超声心动图检查的一部分，因为它可能是唐氏综合征的一个有价值的标志物。
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