没有证据表明丝氨酸蛋白酶抑制剂1（SERPINI1）基因座的基因变异与缺血性中风之间存在关联。 - Suppr

Suppr

超能文献

No evidence for an association between genetic variation at the SERPINI1 locus and ischemic stroke.

作者信息

Tjärnlund-Wolf A, Olsson S, Jood K, Blomstrand C, Jern C

出版信息

J Neurol. 2011 Oct;258(10):1885-7. doi: 10.1007/s00415-011-6022-0. Epub 2011 Apr 13.

DOI:10.1007/s00415-011-6022-0

PMID:21487809

Abstract

摘要

相似文献

No evidence for an association between genetic variation at the SERPINI1 locus and ischemic stroke.没有证据表明丝氨酸蛋白酶抑制剂1（SERPINI1）基因座的基因变异与缺血性中风之间存在关联。

J Neurol. 2011 Oct;258(10):1885-7. doi: 10.1007/s00415-011-6022-0. Epub 2011 Apr 13.

Neuroserpin polymorphisms and stroke risk in a biracial population: the stroke prevention in young women study.

BMC Neurol. 2007 Oct 25;7:37. doi: 10.1186/1471-2377-7-37.

CCM3/SERPINI1 bidirectional promoter variants in patients with cerebral cavernous malformations: a molecular and functional study.脑海绵状血管畸形患者中CCM3/SERPINI1双向启动子变异：一项分子与功能研究

BMC Med Genet. 2016 Oct 13;17(1):74. doi: 10.1186/s12881-016-0332-0.

Genetic variation in complement component C3 shows association with ischaemic stroke.补体成分 C3 中的遗传变异与缺血性中风有关。

Eur J Neurol. 2011 Oct;18(10):1272-4. doi: 10.1111/j.1468-1331.2011.03377.x. Epub 2011 Mar 17.

Increased anxiety was found in serpini1 knockout zebrafish larval.在 serpini1 基因敲除斑马鱼幼虫中发现焦虑增加。

Biochem Biophys Res Commun. 2021 Jan 1;534:1013-1019. doi: 10.1016/j.bbrc.2020.10.048. Epub 2020 Nov 6.

TFPI gene variation and ischemic stroke.组织因子途径抑制物基因变异与缺血性中风。

Thromb Res. 2012 Sep;130(3):565-7. doi: 10.1016/j.thromres.2012.06.011. Epub 2012 Jul 1.

Genetic variation of the androgen receptor and risk of myocardial infarction and ischemic stroke in women.女性雄激素受体的基因变异与心肌梗死和缺血性中风风险

Stroke. 2008 May;39(5):1590-2. doi: 10.1161/STROKEAHA.107.508218. Epub 2008 Mar 6.

Early-onset rapidly progressive myoclonic epilepsy associated with G392R likely pathogenic variant in SERPINI1.早发性快速进展性肌阵挛癫痫与SERPINI1基因中可能致病的G392R变异相关。

Seizure. 2020 Aug;80:181-182. doi: 10.1016/j.seizure.2020.06.022. Epub 2020 Jun 16.

SERPINI1 pathogenic variants: An emerging cause of childhood-onset progressive myoclonic epilepsy.丝氨酸蛋白酶抑制剂I1（SERPINI1）致病变异：儿童期起病的进行性肌阵挛癫痫的一个新出现的病因。

Am J Med Genet A. 2017 Sep;173(9):2456-2460. doi: 10.1002/ajmg.a.38317. Epub 2017 Jun 20.

The association of CYP1A1 genetic polymorphisms and additional gene-gene interaction with ischemic stroke in the eastern Han of China.中国东汉人群中CYP1A1基因多态性及其他基因-基因相互作用与缺血性脑卒中的关联

Neurol Sci. 2016 Oct;37(10):1679-84. doi: 10.1007/s10072-016-2652-4. Epub 2016 Jul 6.

引用本文的文献

Neonatal Hypoxia Ischaemia: Mechanisms, Models, and Therapeutic Challenges.新生儿缺氧缺血：机制、模型与治疗挑战

Front Cell Neurosci. 2017 May 8;11:78. doi: 10.3389/fncel.2017.00078. eCollection 2017.

Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation.神经丝氨酸蛋白酶抑制剂神经抑制素缺乏通过增加缺血后炎症加重缺血性脑损伤。

PLoS One. 2013 May 3;8(5):e63118. doi: 10.1371/journal.pone.0063118. Print 2013.

本文引用的文献

Genetic variation on chromosome 9p21 shows association with the ischaemic stroke subtype large-vessel disease in a Swedish sample aged ≤ 70.9p21 染色体上的遗传变异与瑞典≤70 岁人群的大血管病变缺血性脑卒中亚型相关。

Eur J Neurol. 2011 Feb;18(2):365-367. doi: 10.1111/j.1468-1331.2010.03096.x.

Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke.组织型纤溶酶原激活剂激活血小板衍生生长因子CC会损害缺血性中风期间的血脑屏障完整性。

Nat Med. 2008 Jul;14(7):731-7. doi: 10.1038/nm1787. Epub 2008 Jun 22.

Neuroserpin polymorphisms and stroke risk in a biracial population: the stroke prevention in young women study.

BMC Neurol. 2007 Oct 25;7:37. doi: 10.1186/1471-2377-7-37.

Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit.组织型纤溶酶原激活物介导的星形胶质细胞低密度脂蛋白受体相关蛋白脱落增加了神经血管单元的通透性。

Blood. 2007 Apr 15;109(8):3270-8. doi: 10.1182/blood-2006-08-043125. Epub 2006 Dec 14.

Tissue-type plasminogen activator: a multifaceted modulator of neurotransmission and synaptic plasticity.组织型纤溶酶原激活剂：神经传递和突触可塑性的多面调节因子。

Neuron. 2006 Jun 1;50(5):673-8. doi: 10.1016/j.neuron.2006.04.013.

Family history in ischemic stroke before 70 years of age: the Sahlgrenska Academy Study on Ischemic Stroke.70岁之前缺血性卒中的家族史：哥德堡大学医学院缺血性卒中研究

Stroke. 2005 Jul;36(7):1383-7. doi: 10.1161/01.STR.0000169944.46025.09. Epub 2005 Jun 2.

Tissue plasminogen activator and neuroserpin are widely expressed in the human central nervous system.组织型纤溶酶原激活剂和神经丝氨酸蛋白酶抑制剂在人类中枢神经系统中广泛表达。

Thromb Haemost. 2004 Aug;92(2):358-68. doi: 10.1160/TH02-12-0310.

Equivocal roles of tissue-type plasminogen activator in stroke-induced injury.组织型纤溶酶原激活剂在中风所致损伤中的作用不明确。

Trends Neurosci. 2004 Mar;27(3):155-60. doi: 10.1016/j.tins.2003.12.011.

Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.组织型纤溶酶原激活剂通过低密度脂蛋白受体相关蛋白诱导血脑屏障开放。

J Clin Invest. 2003 Nov;112(10):1533-40. doi: 10.1172/JCI19212.

Neuroserpin, a neuroprotective factor in focal ischemic stroke.神经丝氨酸蛋白酶抑制剂，局灶性缺血性卒中的一种神经保护因子。

Mol Cell Neurosci. 2001 Nov;18(5):443-57. doi: 10.1006/mcne.2001.1028.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验