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NOTES 中经皮内镜下胃造口术(STAT)自逼近经腔入路技术进行胃腔入口封闭的可靠性。

Reliability of gastric access closure with the self-approximating transluminal access technique (STAT) for NOTES.

机构信息

Division of Gastroenterology, Penn State Hershey Medical Center and Penn State College of Medicine, Hershey, PA 17033, USA.

出版信息

Surg Endosc. 2011 Aug;25(8):2718-24. doi: 10.1007/s00464-011-1659-4. Epub 2011 Apr 13.

DOI:10.1007/s00464-011-1659-4
PMID:21487879
Abstract

BACKGROUND

STAT, or the self-approximating transluminal access technique, has been previously described and involves the dissection of a submucosal tunnel for peritoneal or mediastinal access from the esophagus and stomach. The objective of this study was to assess the safety and reliability of gastric access and closure in a porcine experience using STAT for natural orifice transluminal endoscopic surgery (NOTES).

METHODS

A review of the experience using STAT access tunnels for intraperitoneal access was performed in 39 female pigs at a university animal lab. All animals underwent a predetermined NOTES surgical procedure using a STAT transgastric access tunnel based on a specific protocol. Details of the procedure, complications, and clinical course were documented. Necropsy was performed at 2 weeks. The main outcome measurements were clinical or necropsy evidence of gastrostomy site leak or inadequate access site closure.

RESULTS

STAT was successful in providing safe peritoneal access in all animals. The width of the tunnel ranged from 1.5 to 5.5 cm and the length was up to 27 cm. There was no evidence of gastrostomy site leak in any animals. One animal required a single laparoscopic suture to help with tunnel closure.

CONCLUSION

STAT provides safe transgastric access and allows secure closure of the gastrotomy site.

摘要

背景

STAT,即自逼近经腔入路技术,此前已有描述,涉及从食管和胃中解剖出用于腹膜或纵隔入路的黏膜下隧道。本研究的目的是评估使用 STAT 进行经自然腔道内镜手术(NOTES)时,猪模型中胃入路和闭合的安全性和可靠性。

方法

在大学动物实验室,对 39 头雌性猪进行了使用 STAT 入路隧道进行腹膜内入路的经验回顾。所有动物均按照特定方案,使用 STAT 经胃入路隧道进行了预定的 NOTES 手术。记录了手术过程、并发症和临床经过的详细情况。在 2 周时进行尸检。主要观察指标为胃造口部位漏出或入路部位闭合不足的临床或尸检证据。

结果

STAT 成功地为所有动物提供了安全的腹膜内入路。隧道的宽度为 1.5 至 5.5 厘米,长度可达 27 厘米。没有动物出现胃造口部位漏出的证据。有 1 只动物需要单针腹腔镜缝线帮助闭合隧道。

结论

STAT 提供了安全的经胃入路,并允许安全闭合胃造口部位。

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Surg Endosc. 2011 Jan;25(1):315-21; discussion 321-2. doi: 10.1007/s00464-010-1141-8. Epub 2010 Aug 20.
2
Peroral endoscopic myotomy (POEM) for esophageal achalasia.经口内镜下肌切开术(POEM)治疗食管失弛缓症。
Endoscopy. 2010 Apr;42(4):265-71. doi: 10.1055/s-0029-1244080. Epub 2010 Mar 30.
3
Directed submucosal tunneling permits in-line endoscope positioning for transgastric natural orifice translumenal endoscopic surgery (NOTES).
Intramural acellular porcine dermal matrix (APDM)-assisted gastrotomy closure for natural orifice transluminal endoscopic surgery (NOTES).
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Surg Endosc. 2012 Aug;26(8):2322-30. doi: 10.1007/s00464-012-2183-x. Epub 2012 Feb 23.
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Surg Endosc. 2010 Jun;24(6):1474-81. doi: 10.1007/s00464-009-0760-4. Epub 2009 Dec 24.
4
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Endoscopic closure of gastric access in perspective NOTES: an update on techniques and technologies.内镜下胃造口闭合术:NOTES 技术的现状与展望——技术与方法更新。
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