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[前列腺多参数磁共振成像——技术与临床应用]

[Multiparametric magnetic resonance imaging of the prostate - technique and clinical applications].

作者信息

Franiel T

机构信息

Radiologie CCM, Charité - Universitätsmedizin Berlin.

出版信息

Rofo. 2011 Jul;183(7):607-17. doi: 10.1055/s-0029-1246055. Epub 2011 Apr 12.

DOI:10.1055/s-0029-1246055
PMID:21487980
Abstract

Multiparametric magnetic resonance imaging (MRI) includes 1 H magnetic resonance spectroscopy, diffusion-weighted imaging, and dynamic contrast-enhanced MRI. These new MRI techniques are increasingly being used to supplement conventional T 2 and T 1-weighted MR sequences in prostate imaging. The first part of this review outlines each of these techniques, the most important diagnostic parameters, and the pathophysiological background. The characteristic features of prostate cancer and noncancerous prostate tissue as depicted with each of the three techniques are presented. The second, clinical part outlines the diagnostic applications of the three MRI techniques for the early detection and localization of prostate cancer, staging, and the identification of recurrent cancer and discusses the most recent publications in this field. The review concludes with a look at emerging clinical applications such as the evaluation of biological aggressiveness and tumor volume.

摘要

多参数磁共振成像(MRI)包括氢质子磁共振波谱、扩散加权成像和动态对比增强MRI。这些新的MRI技术越来越多地用于补充前列腺成像中传统的T2加权和T1加权MR序列。本综述的第一部分概述了每种技术、最重要的诊断参数以及病理生理背景。介绍了用这三种技术中的每一种所描绘的前列腺癌和非癌性前列腺组织的特征。第二部分,临床部分概述了这三种MRI技术在前列腺癌早期检测和定位、分期以及复发性癌症识别方面的诊断应用,并讨论了该领域的最新出版物。综述最后展望了诸如生物侵袭性评估和肿瘤体积评估等新兴临床应用。

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