Barzin Ario, Hernandez-Boussard Tina, Lee Gordon K, Curtin Catherine
Division of Plastic and Reconstructive Surgery and Department of Surgery, Stanford University Medical Center, Stanford, CA 94304, USA.
J Hand Surg Am. 2011 May;36(5):870-4. doi: 10.1016/j.jhsa.2011.01.031. Epub 2011 Apr 12.
The decision to proceed with digital replantation in the elderly can be challenging. In addition to success of the replanted part, perioperative morbidity and mortality must be considered. The purpose of this study was to compare adverse events in patients less than 65 years of age compared with those 65 years and older after digital replantation. We hypothesize that there is an increased incidence of mortality and sentinel adverse events in patients aged 65 and older.
We obtained data from the Nationwide Inpatient Sample over a 10-year period from 1998 to 2007. Replantation was identified using International Classification of Diseases-9 procedure codes for finger and thumb reattachment (84.21 and 84.22). Adverse events were identified using Patient Safety Indicators (PSI) to identify adverse events occurring during hospitalization. We used the Charlson index to study medical comorbidities and bivariate statistics.
During the study period 15,413 finger and thumb replantations were performed in the United States, with 616 performed on patients age 65 and older. The overall in-hospital mortality was 0.04% with no statistical difference when factoring age. For the entire group, the percentage of PSI was 0.6%, the most common being postoperative deep venous thrombosis and pulmonary embolus. Overall, there was no difference in PSI between the 2 groups. The older group had a higher rate of transfusion, 4% versus 8% (p < .05) and were more likely to have a nonroutine disposition (ie, nursing home) (p < .001). We found no correlation between the Charlson index and PSI.
This study found no difference in sentinel perioperative complications or mortality when comparing replantation patients under 65 years of age and those age 65 and older. Age alone should not be an absolute contraindication to finger replantation. Instead, the patient's functional demands, type of injury, general state of health, and rehabilitative potential should drive the decision of whether to proceed with replantation.
决定是否对老年人进行断指再植具有挑战性。除了再植部位的成功之外,还必须考虑围手术期的发病率和死亡率。本研究的目的是比较年龄小于65岁与65岁及以上患者断指再植后的不良事件。我们假设65岁及以上患者的死亡率和标志性不良事件的发生率会增加。
我们从1998年至2007年的10年期间的全国住院患者样本中获取数据。使用国际疾病分类第9版程序代码(84.21和84.22)识别手指和拇指再植情况。使用患者安全指标(PSI)识别住院期间发生的不良事件。我们使用查尔森指数研究医疗合并症和双变量统计。
在研究期间,美国共进行了15413例手指和拇指再植手术,其中616例是在65岁及以上的患者中进行的。总体住院死亡率为0.04%,考虑年龄因素后无统计学差异。对于整个组,PSI的百分比为0.6%,最常见的是术后深静脉血栓形成和肺栓塞。总体而言,两组之间的PSI没有差异。老年组的输血率更高,分别为4%和8%(p <.05),并且更有可能有非常规处置(即疗养院)(p <.001)。我们发现查尔森指数与PSI之间没有相关性。
本研究发现,比较65岁以下和65岁及以上的再植患者,围手术期标志性并发症或死亡率没有差异。仅年龄不应成为手指再植的绝对禁忌症。相反,患者的功能需求、损伤类型、总体健康状况和康复潜力应驱动是否进行再植的决定。