Department of Psychiatry, Kulliyyah of Medicine, International Islamic University Malaysia, Bandar Indera Mahkota, Kuantan, Pahang, Malaysia
Asia Pac J Public Health. 2012 Sep;24(5):826-32. doi: 10.1177/1010539511404396. Epub 2011 Apr 13.
The commencement of methadone maintenance therapy (MMT) in 2005 represents a quantum leap in the management of heroin dependence in Malaysia.
To examine the 2-year outcomes of this modality in the treatment of heroin dependence with respect to the quality of life (QOL), heroin abstinence, and rate of employment among heroin dependants attending the Tengku Ampuan Afzan Hospital (HTAA) MMT clinic.
This was an experimental study in which the second QOL assessment was conducted 2 years after treatment initiation.
A total of 172 patients enrolled at the point of entry to the MMT program. The authors examined 107 patients who remained in the program 2 years later (62.6% retention rate). A paired t test demonstrated significant improvements in all 4 domains of QOL (physical, psychological, social relationships, and environment; P < .001). The most marked improvement was noted in the psychological domain.
The MMT program at HTAA is effective in improving the QOL among heroin dependants.
2005 年美沙酮维持治疗(MMT)的开展标志着马来西亚在治疗海洛因成瘾方面取得了重大突破。
通过对接受登嘉楼州皇后医院(HTAA)美沙酮维持治疗门诊治疗的海洛因成瘾者的生活质量(QOL)、海洛因戒除率和就业率进行评估,研究该模式治疗海洛因成瘾的 2 年结果。
这是一项实验性研究,在治疗开始后 2 年进行了第二次 QOL 评估。
共有 172 名患者在进入 MMT 项目时入组。作者检查了 2 年后仍留在该项目中的 107 名患者(保留率为 62.6%)。配对 t 检验显示,QOL 的所有 4 个领域(身体、心理、社会关系和环境)均有显著改善(P<0.001)。心理领域的改善最为显著。
HTAA 的 MMT 项目在改善海洛因成瘾者的生活质量方面是有效的。