Increasing interest in PK and PD studies has many advantages for anesthesiologists.
作者信息
Woo Young-Cheol
机构信息
Department of Anesthesiology and Pain Medicine, Chung-Ang University Hospital, Seoul, Korea.
出版信息
Korean J Anesthesiol. 2011 Mar;60(3):149-50. doi: 10.4097/kjae.2011.60.3.149. Epub 2011 Mar 30.
Abstract
摘要
相似文献
1
Increasing interest in PK and PD studies has many advantages for anesthesiologists.对药代动力学（PK）和药效动力学（PD）研究日益增长的兴趣对麻醉医生有诸多益处。
Korean J Anesthesiol. 2011 Mar;60(3):149-50. doi: 10.4097/kjae.2011.60.3.149. Epub 2011 Mar 30.
2
A new fully human recombinant FSH (follitropin epsilon): two phase I randomized placebo and comparator-controlled pharmacokinetic and pharmacodynamic trials.一种新的完全人重组 FSH（卵泡刺激素 ε）：两项 I 期随机安慰剂和对照药比较的药代动力学和药效学研究。
Hum Reprod. 2017 Aug 1;32(8):1639-1647. doi: 10.1093/humrep/dex220.
3
Integration and modelling of pharmacokinetic and pharmacodynamic data to optimize dosage regimens in veterinary medicine.整合与模拟药代动力学和药效学数据以优化兽医药剂方案。
J Vet Pharmacol Ther. 2004 Dec;27(6):467-77. doi: 10.1111/j.1365-2885.2004.00613.x.
4
Application of microdialysis for pharmacokinetic-pharmacodynamic modelling.微透析在药代动力学-药效学建模中的应用。
Expert Opin Drug Discov. 2006 Sep;1(4):289-301. doi: 10.1517/17460441.1.4.289.
5
Microdialysis for pharmacokinetic-pharmacodynamic studies.用于药代动力学-药效学研究的微透析技术。
Pharmazie. 2007 Dec;62(12):883-91.
6
PK-PD Compass: bringing infectious diseases pharmacometrics to the patient's bedside.PK-PD指南针：将感染性疾病药物计量学应用于患者床边
J Pharmacokinet Pharmacodyn. 2017 Apr;44(2):161-177. doi: 10.1007/s10928-017-9518-0. Epub 2017 Mar 28.
7
PK-PD integration and PK-PD modelling of nonsteroidal anti-inflammatory drugs: principles and applications in veterinary pharmacology.非甾体抗炎药的药代动力学-药效学整合与药代动力学-药效学建模：原理及其在兽医药理学中的应用
J Vet Pharmacol Ther. 2004 Dec;27(6):491-502. doi: 10.1111/j.1365-2885.2004.00618.x.
8
Modeling Pharmacokinetics and Pharmacodynamics of Therapeutic Antibodies: Progress, Challenges, and Future Directions.治疗性抗体的药代动力学和药效学建模：进展、挑战与未来方向
Pharmaceutics. 2021 Mar 21;13(3):422. doi: 10.3390/pharmaceutics13030422.
9
Volterra series in pharmacokinetics and pharmacodynamics.药代动力学和药效学中的沃尔泰拉级数
J Pharmacokinet Pharmacodyn. 2003 Oct;30(5):337-62. doi: 10.1023/b:jopa.0000008158.30235.59.
10
Pharmacodynamics and pharmacokinetics of nonsteroidal anti-inflammatory drugs in species of veterinary interest.非甾体抗炎药在兽医关注物种中的药效学和药代动力学。
J Vet Pharmacol Ther. 2004 Dec;27(6):479-90. doi: 10.1111/j.1365-2885.2004.00617.x.
本文引用的文献
1
The BIS and hemodynamic changes in major burn patients according to a slow infusion of propofol for induction.根据异丙酚缓慢输注诱导的主要烧伤患者的 BIS 和血流动力学变化。
Korean J Anesthesiol. 2011 Mar;60(3):161-6. doi: 10.4097/kjae.2011.60.3.161. Epub 2011 Mar 30.
2
Early drug distribution: a generally neglected aspect of pharmacokinetics of particular relevance to intravenously administered anesthetic agents.早期药物分布：药代动力学中一个普遍被忽视的方面，对静脉注射麻醉剂尤为重要。
Clin Pharmacol Ther. 2008 Jul;84(1):18-22. doi: 10.1038/clpt.2008.107.
3
Anesthesia: a discipline that incorporates clinical pharmacology across the DDRU continuum.
Clin Pharmacol Ther. 2008 Jul;84(1):3-6. doi: 10.1038/clpt.2008.99.
4
Contributions of PK/PD modeling to intravenous anesthesia.药代动力学/药效学建模对静脉麻醉的贡献。
Clin Pharmacol Ther. 2008 Jul;84(1):27-38. doi: 10.1038/clpt.2008.100. Epub 2008 May 7.
5
Pharmacokinetics and pharmacodynamics of intravenously administered anesthetic drugs: concepts and lessons for drug development.静脉注射麻醉药物的药代动力学和药效学：药物研发的概念与经验教训
Clin Pharmacol Ther. 2008 Jul;84(1):153-7. doi: 10.1038/clpt.2008.80. Epub 2008 May 7.
6
Pharmacokinetics and pharmacodynamics of propofol microemulsion and lipid emulsion after an intravenous bolus and variable rate infusion.丙泊酚微乳剂和脂质乳剂静脉推注及可变速率输注后的药代动力学和药效学
Anesthesiology. 2007 May;106(5):924-34. doi: 10.1097/01.anes.0000265151.78943.af.
7
The fate of thiopental in man and a method for its estimation in biological material.硫喷妥在人体中的代谢情况及其在生物材料中的测定方法。
J Pharmacol Exp Ther. 1950 Jan;98(1):85-96.
8
Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine.药代动力学和药效学的同步建模：应用于筒箭毒碱。
Clin Pharmacol Ther. 1979 Mar;25(3):358-71. doi: 10.1002/cpt1979253358.
9
A pharmacodynamic model for pancuronium.泮库溴铵的药效学模型。
Br J Anaesth. 1978 Nov;50(11):1113-23. doi: 10.1093/bja/50.11.1113.
Zotero 插件