Sane Jussi, Kurkela Satu, Vapalahti Olli
Helsingin yliopisto, Haartman-instituutti, virologian osasto, Helsingin yliopisto.
Duodecim. 2011;127(5):457-63.
Chikungunya virus, originating from Africa, hit the headlines in 2004 upon causing a large-scale epidemic. Typical symptoms of chikungunya virus infection include severe joint aches, high fever and skin rash. Increased incidence of neurologic symptoms was noted in connection with the epidemic of the recent years, and deaths were also reported. A single point mutation in the viral genome enabled an effective multiplication of the virus in a species of mosquito (Aedes albopictus) that was new to the virus. During the last decades, this species of mosquito has spread into Southern Europe, and the spreading is likely to continue.
基孔肯雅病毒起源于非洲，在2004年引发大规模疫情后成为头条新闻。基孔肯雅病毒感染的典型症状包括严重的关节疼痛、高烧和皮疹。近年来的疫情中出现了神经症状发病率增加的情况，也有死亡报告。病毒基因组中的一个单点突变使该病毒能够在一种对其而言全新的蚊子（白纹伊蚊）中有效繁殖。在过去几十年里，这种蚊子已经扩散到南欧，而且这种扩散很可能会持续下去。
