Karikoski Riitta
HUSLAB, Meilahden laboratoriot, patologian keskuslaboratorio PL 400, 00029 HUS.
Duodecim. 2011;127(5):464-72.
Histopathological examinations of the placenta can reveal ischemic changes, inflammation of the placenta and fetal membranes, and changes indicating fetal anemia. These may be a threat to the fetus or cause later complications during childhood. Chronic villositis is caused by a maternal rejection reaction against fetal antigens. This rejection may cause retardation of fetal growth. Early preeclampsia causes severe ischemic changes to the placenta. The placenta should always be examined if the growth of the fetus is abnormal, if the fetus is stillborn, if the neonate exhibits a congenital disease, or in cases of suspected infection.
胎盘的组织病理学检查可揭示缺血性改变、胎盘及胎膜炎症,以及提示胎儿贫血的变化。这些情况可能对胎儿构成威胁,或导致儿童期后期出现并发症。慢性绒毛炎由母体对胎儿抗原的排斥反应引起。这种排斥可能导致胎儿生长发育迟缓。早期先兆子痫会使胎盘发生严重缺血性改变。如果胎儿生长异常、胎儿死产、新生儿患有先天性疾病或存在疑似感染的情况,均应始终对胎盘进行检查。