Alexa Ioana Dana, Bucur Ionela Mirela, Rusu R I, Ungureanu G
Department of Internal Medicine, School of Medicine, Gr.T. Popa University of Medicine and Pharmacy Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2009 Apr-Jun;113(2):376-81.
Atrial fibrillation (AF), a common and serious cardiac rhythm disturbance, is responsible for substantial morbidity and mortality in the population. Currently about 2.3 million people in the US are diagnosed with AF and, based of the US census, this number is expected to rise to 5.6 million by 2050. It doubles in prevalence with each decade of age, reaching almost 9% at age 80-89 years. It has increased in prevalence over the calendar decades, reaching 'epidemic' proportions. The risk of stroke increases from 1.5% in patients with atrial fibrillation from 50-59 years of age to up to 23.5% for such patients aged 80-89 years. Although the diagnosis of atrial fibrillation is usually straightforward, effective treatment is not. We aimed to discuss how rhythm control of atrial fibrillation can best be achieved in elderly patients, the controversy over the rhythm versus rate control, and prevention of thromboembolism.
心房颤动（AF）是一种常见且严重的心律失常，是导致人群中大量发病和死亡的原因。目前美国约有230万人被诊断为心房颤动，根据美国人口普查，预计到2050年这一数字将增至560万。其患病率每增长十岁便会翻倍，在80 - 89岁时几乎达到9%。在过去几十年中其患病率不断上升，已达到“流行”程度。心房颤动患者的中风风险从50 - 59岁时的1.5%增至80 - 89岁患者的高达23.5%。虽然心房颤动的诊断通常很简单，但有效的治疗并非如此。我们旨在探讨如何在老年患者中最佳地实现心房颤动的节律控制、节律控制与心率控制的争议以及血栓栓塞的预防。
