Novăcescu P, Clonda M
Secţia A.T.I., Spitalul Municipal Lugoj.
Rev Chir Oncol Radiol O R L Oftalmol Stomatol Chir. 1990 Jan-Feb;39(1):67-70.
The authors carried out a study on patients in whom spinal anaesthesia was performed for various surgical procedures. In a first group of patients neither ephedrine nor other sympathicomimetic drugs were administered before spinal anaesthesia, while in the second group ephedrine was given on a systematic basis as premedication, with the exception of patients who had an absolute contraindication for this drug. In the first group headache following spinal anaesthesia was much more frequent and it was inferred that hypotension with consecutive hypoxia could be considered as a pathophysiological mechanism of headache, beside the already known and accepted mechanisms.
作者对因各种外科手术接受脊髓麻醉的患者进行了一项研究。在第一组患者中，脊髓麻醉前未给予麻黄碱或其他拟交感神经药物，而在第二组中，除了对该药物有绝对禁忌证的患者外，麻黄碱作为术前用药被系统给药。在第一组中，脊髓麻醉后头痛更为常见，据此推断，除了已知且被认可的机制外，连续缺氧导致的低血压可被视为头痛的病理生理机制。
