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[维生素C缺乏症豚鼠组织中儿茶酚胺和皮质类固醇的含量]

[Contents of catecholamines and corticosteroids in tissues of quinea pigs with C-hypovitaminosis].

作者信息

Lesnykh L D, Laskavaia A I

出版信息

Ukr Biokhim Zh (1978). 1978 Sep-Oct;50(5):592-5.

PMID:214920
Abstract

On the 12-14th day of the scorbutigenic regime simultaneously with a decrease in the level of ascorbic acid in the guinea pig tissues to content of catecholamines and 11-oxycorticosteroids changes as well. The amount of adrenalin in the adrenal tissue drops, that of epinephrine in the brain tissue and liver rises. The content of glucocorticoids in adrenals and blood plasm increases. Against a background of vitamin C deficiency administration of ACTH does not cause any deviations in the level of catecholamines in tissues, of 11-oxycorticosteroids in the adrenals tissue and increase insignificantly the content of the latter in blood plasm.

摘要

在致坏血病方案实施的第12 - 14天,豚鼠组织中抗坏血酸水平下降的同时,儿茶酚胺和11 - 氧皮质类固醇的含量也发生变化。肾上腺组织中肾上腺素的量减少,脑组织和肝脏中肾上腺素的量增加。肾上腺和血浆中糖皮质激素的含量增加。在维生素C缺乏的背景下,给予促肾上腺皮质激素不会导致组织中儿茶酚胺水平、肾上腺组织中11 - 氧皮质类固醇水平出现任何偏差,且只会使血浆中后者的含量略有增加。

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