Ahlberg Alexander, Engström Therese, Nikolaidis Polymnia, Gunnarsson Karin, Johansson Hemming, Sharp Lena, Laurell Göran
Department of Otolaryngology, Karolinska University Hospital, Stockholm, Sweden.
Acta Otolaryngol. 2011 May;131(5):552-61. doi: 10.3109/00016489.2010.532157.
No positive effects of early preventive rehabilitation could be identified. The results do not contradict the proposition that rehabilitation based on self-care can be effective but it is important to establish evidence-based training programs and identify proper instruments for selection of patients and evaluation of intervention.
Patients with head and neck cancer suffer from functional impairments due to intense treatment. In this study, we investigated the effectiveness of an experimental early preventive rehabilitation using hard, objective end points in a nonselective, longitudinal, prospective cohort study.
In all, 190 patients were included in the program and received instructions for training before the start of treatment with the aim of reducing swallowing problems and reducing mouth opening and stiffness in the neck. A control group of 184 patients was recruited.
There was no difference in weight loss and 2-year survival between the two groups. No positive effects concerning functional impairments were found in patient-reported outcome measures.
未发现早期预防性康复有积极效果。研究结果并不与基于自我护理的康复可能有效的观点相矛盾，但重要的是要建立循证培训计划，并确定用于患者选择和干预评估的合适工具。
头颈癌患者因强化治疗而出现功能障碍。在本研究中，我们在一项非选择性、纵向、前瞻性队列研究中，使用严格、客观的终点指标，调查了一项实验性早期预防性康复的效果。
共有190名患者纳入该项目，并在治疗开始前接受训练指导，目的是减少吞咽问题，减轻颈部张口困难和僵硬。招募了184名患者作为对照组。
两组之间在体重减轻和2年生存率方面没有差异。在患者报告的结局指标中，未发现功能障碍方面的积极效果。
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