分析辐照对牙种植体骨整合的影响。

Analysis of the effects of irradiation in osseointegrated dental implants.

机构信息

Department of Materials and Technology, UNESP, Univ. Estadual Paulista, Guaratinguetá Campus, Guaratinguetá, SP, Brazil.

出版信息

Clin Oral Implants Res. 2012 Apr;23(4):511-4. doi: 10.1111/j.1600-0501.2010.02149.x. Epub 2011 Apr 15.

DOI:10.1111/j.1600-0501.2010.02149.x

PMID:21492234

Abstract

OBJECTIVE

The purpose of the present study was to evaluate the influence of radiation in osseointegrated dental implants installed in tibiae of rats.

MATERIAL AND METHODS

Screw-shaped implants (2.5 mm diameter by 3.5 mm length) were custom made from commercially pure titanium bars. Titanium implants were blasted and sterilized before implantation. Animals were divided into two groups of 12 animals each and the rats were not paired after the groups' formation. The experimental group (group 1) received external irradiation 4 weeks after surgery while in the control group (group 2) animals were kept free of radiation. The shear strength required to detach the implant from bone was measured by push-out testing and osseointegration was histologically evaluated.

RESULTS

Results showed that the compressive strength of irradiated implants (33.49 MPa) was significantly lower than the compressive strength of non-irradiated implants (48.05 MPa).

CONCLUSIONS

We concluded that the mechanical strength bonding between implants and host tissues decreased after irradiation.

摘要

目的

本研究旨在评估植入大鼠胫骨中的骨整合牙科种植体的辐射影响。

材料与方法

定制了由商用纯钛棒制成的螺纹状种植体（直径 2.5 毫米，长 3.5 毫米）。在植入前，对钛种植体进行了喷砂和消毒。动物分为两组，每组 12 只，分组后不配对。实验组（第 1 组）在手术后 4 周接受外部照射，而对照组（第 2 组）动物不受辐射影响。通过推出试验测量了从骨上分离植入物所需的剪切强度，并对骨整合进行了组织学评估。