Department of Oral Medicine and Orofacial Surgery, Faculty of Odontology, Complutense University, Madrid, SpainDepartment of Health Sciences III, Faculty of Health Sciences, Rey Juan Carlos University, Alcorcón, SpainDepartment of Oral and Maxillofacial Surgery, University Hospital of Asturias, Faculty of Medicine and Dentistry, Oviedo, Spain.
Clin Oral Implants Res. 2012 Jun;23(6):726-732. doi: 10.1111/j.1600-0501.2011.02192.x. Epub 2011 Apr 15.
The main aim of this prospective-controlled study was to evaluate the implant survival rate in patients diagnosed with oral lichen planus (OLP). The secondary goals were to analyze the presence of implant- and patient-dependent variables.
Two groups, including 18 patients diagnosed with OLP and 18 controls, received 56 and 62 implants during the years 2003-2008. Pain and wound healing were evaluated after the procedure. After a mean follow-up of 53.5 and 52.3 months, clinical and radiographic assessments were used to evaluate implant survival and patient- and implant-dependent parameters.
The implant survival rate was 100% for the OLP group. Immediate postsurgical complications were similar in both groups. Peri-implant mucositis (PIM) was detected in 44.6% of the implants and 66.6% of the patients with OLP. The presence of desquamative gingivitis (DG) was associated with a higher rate of PIM on those implants of the OLP group (P=0.004). Peri-implantitis (PI) appeared in 10.7% of the implants and 27.7% of the patients with OLP (P=NS).
Despite the limitations of the small sample size, it seems that lichen planus is not a prominent local player in the genesis of implant failure. Patients with DG should be carefully examined during follow-up care.
本前瞻性对照研究的主要目的是评估诊断为口腔扁平苔藓（OLP）患者的种植体存活率。次要目标是分析种植体和患者相关变量的存在情况。
2003 年至 2008 年间，共纳入 18 例 OLP 患者和 18 例对照组患者，分别接受了 56 颗和 62 颗种植体。术后评估疼痛和伤口愈合情况。平均随访 53.5 个月和 52.3 个月后，采用临床和影像学评估来评估种植体存活率以及患者和种植体相关参数。
OLP 组的种植体存活率为 100%。两组的即刻术后并发症相似。OLP 组中 44.6%的种植体和 66.6%的患者出现了种植体周围黏膜炎（PIM）。患有剥脱性龈炎（DG）的患者在 OLP 组中 PIM 发生率更高（P=0.004）。10.7%的种植体和 27.7%的 OLP 患者出现了种植体周围炎（PI）（P=NS）。
尽管样本量较小存在局限性，但似乎扁平苔藓并不是导致种植体失败的主要局部因素。在随访期间，应仔细检查患有 DG 的患者。
