Division of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Oral Dis. 2024 Sep;30(6):3850-3865. doi: 10.1111/odi.14964. Epub 2024 May 12.
This study aimed to evaluate the incidence of implant failure in patients with oral lichen planus (OLP) and investigate the potential association between OLP and peri-implant diseases.
Embase, Web of Science, PubMed, and Scopus databases were searched for studies with no time restrictions. Meta-analysis was performed calculating pooled proportion of peri-implantitis (PI), peri-implant mucositis (PIM), and bleeding on probing (BOP) prevalence using fixed-effects model. Odds ratio and corresponding 95% CI were calculated to assess the potential risk of PI, PIM, and BOP in dental implant patients with OLP compared to healthy controls.
Implant failure rate was 4.38% at the patient level and 4.37% at the implant level. Six patients (3.92%) from five studies were diagnosed with oral cancer after receiving implant. The prevalence of PI, PIM, and BOP at the implant level were 14.00%, 20.00%, and 40.00%, respectively. There was no significant difference in the occurrence of PI and PIM between OLP patients and healthy controls.
Stabilized OLP is not considered a significant risk factor for peri-implant diseases. It is advised against placing implants or prostheses during the acute phase of the disease. Histopathological investigation to differentiate OLP from oral lichenoid dysplasia is crucial.
本研究旨在评估口腔扁平苔藓(OLP)患者种植体失败的发生率,并探讨 OLP 与种植体周围疾病之间的潜在关联。
无时间限制地检索了 Embase、Web of Science、PubMed 和 Scopus 数据库中的研究。使用固定效应模型计算了种植体周围炎(PI)、种植体周围黏膜炎(PIM)和探诊出血(BOP)的患病率,并进行了荟萃分析。计算了比值比(OR)及其 95%置信区间(CI),以评估与健康对照组相比,患有 OLP 的种植牙患者发生 PI、PIM 和 BOP 的潜在风险。
患者层面的种植体失败率为 4.38%,种植体层面的种植体失败率为 4.37%。五篇研究中有六名患者(3.92%)在接受种植体后被诊断为口腔癌。种植体水平的 PI、PIM 和 BOP 的患病率分别为 14.00%、20.00%和 40.00%。OLP 患者与健康对照组之间,PI 和 PIM 的发生无显著差异。
稳定期 OLP 不被认为是种植体周围疾病的显著危险因素。建议在疾病的急性阶段不进行种植体或义齿的放置。区分 OLP 与口腔扁平苔藓样变的组织病理学检查至关重要。