Department of Infectious Disease Control, Antwerp, Belgium.
Euro Surveill. 2011 Apr 7;16(14):19838.
In the beginning of April 2008 three cases of Shigella sonnei infection were identified among the Orthodox Jewish community of Antwerp, Belgium. We conducted a descriptive study and a household cohort study to identify potential risk factors. Stool samples were cultured and antibiotic susceptibility of the isolates was determined. Between April and August 2008, 42 cases were registered. All characterised isolates (n=20) shared an identical pulsed-field gel electrophoresis profile and were indistinguishable from one of the twelve main strains detected in Israel in 2008, where the index case's father had stayed before the outbreak. The secondary attack rate in households was 8.5% (95% confidence interval (CI): 4.3–12.7). Multivariate analysis identified the following risk factors for secondary spread: households with more than three children (adjusted relative risk (RR): 9.17; 95% CI: 1.21–69.13), children younger than five years (adjusted RR: 5.45; 95% CI: 2.44–12.62), and children younger than 12 years assisting in washing younger siblings (adjusted RR: 5.45; 95% CI: 2.44–12.17). Rigorous hand washing, use of disposable towels, information for parents and caregivers, and exclusion of symptomatic children from day care, preschool and school for a minimum of 48 hours were implemented.
2008 年 4 月初，比利时安特卫普的正统犹太社区发现了 3 例宋内志贺菌感染病例。我们开展了一项描述性研究和家庭队列研究，以确定潜在的危险因素。采集粪便样本进行培养，并确定分离株的抗生素敏感性。2008 年 4 月至 8 月期间，共登记了 42 例病例。所有特征明确的分离株（n=20）具有相同的脉冲场凝胶电泳图谱，与 2008 年在以色列检测到的 12 个主要菌株之一无法区分，索引病例的父亲在疫情爆发前曾在那里逗留。家庭中的二次攻击率为 8.5%（95%置信区间（CI）：4.3-12.7）。多变量分析确定了以下二级传播的危险因素：家中有 3 个以上儿童（调整后的相对风险（RR）：9.17；95%CI：1.21-69.13）、5 岁以下儿童（调整 RR：5.45；95%CI：2.44-12.62）和 12 岁以下的儿童帮助清洗年龄较小的兄弟姐妹（调整 RR：5.45；95%CI：2.44-12.17）。我们实施了严格的洗手、使用一次性毛巾、向家长和照顾者提供信息以及将有症状的儿童从日托、学前班和学校中排除至少 48 小时等措施。
