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A phase I study of toremifene.

作者信息

Tominaga T, Abe O, Izuo M, Nomura Y

机构信息

Tokyo Metropolitan Komagome Hospital, Japan.

出版信息

Breast Cancer Res Treat. 1990 Aug;16 Suppl:S27-9. doi: 10.1007/BF01807141.

Abstract

A Phase I study of the new antiestrogenic drug toremifene was carried out in 27 Japanese women, using oral doses of 10-480 mg per day for one or five days. Serum concentrations reached a dose-dependent maximum 2-6 hours after each oral administration. Side effects were generally mild.

摘要

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