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PACU 甲状旁腺素有助于安全的门诊全甲状腺切除术。

PACU PTH facilitates safe outpatient total thyroidectomy.

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio 45267-0528, USA.

出版信息

Otolaryngol Head Neck Surg. 2011 Jan;144(1):43-7. doi: 10.1177/0194599810390453.

Abstract

OBJECTIVE

To determine if a serum parathyroid hormone (PTH)-based discharge algorithm can be used to safely facilitate outpatient total thyroidectomy.

STUDY DESIGN

Case series with chart review of consecutive total and completion thyroidectomies performed by the senior author from March 2008 to November 2009.

SETTING

An academic tertiary care center.

SUBJECTS AND METHODS

At the authors' institution, patients undergoing total or completion thyroidectomy are subject to a same-day discharge algorithm that incorporates postanesthesia care unit rapid PTH as the major discharge criterion. Patients with PTH >30 pg/mL are eligible for same-day discharge without supplementation, patients with PTH between 20 and 30 pg/mL are eligible for discharge but receive calcium supplementation, and patients with PTH <20 pg/mL are observed overnight (23 hours) with calcium and vitamin D supplementation.

RESULTS

One hundred eighty patients (mean age, 48.9 years; 83.3% female) underwent total (77.2%) or completion (22.7%) thyroidectomy with or without node dissection. Forty-two percent were performed with minimally invasive video-assisted (MIVA) technique. Seventy-six percent (137/180) of patients had a PTH >20 pg/mL, meeting the PTH discharge criterion. Sixty-nine percent (95/137) of eligible patients were discharged on the same day (53.1% of total). Ten percent of discharge-eligible patients were admitted due to drain placement. Of the 95 patients undergoing outpatient surgery, none were admitted, seen, or called for symptoms of hypocalcemia in the postoperative period. All 180 patients were eucalcemic at postoperative day (POD) 7 and POD 30 office visits. No patients were hypoparathyroid at POD 30. No significant difference in postoperative hypoparathyroidism existed between completion versus total thyroidectomy (11.1% vs 22.2%, P = .28) or MIVA versus standard technique (P = .37).

CONCLUSION

A PTH-based discharge algorithm can safely facilitate outpatient total or completion thyroidectomy, with minimal risk of clinically significant outpatient hypocalcemia.

摘要

目的

确定基于甲状旁腺激素(PTH)的出院算法是否可用于安全促进门诊全甲状腺切除术。

研究设计

对 2008 年 3 月至 2009 年 11 月由资深作者进行的连续全甲状腺切除术和完成甲状腺切除术的病例系列进行图表回顾。

设置

学术三级护理中心。

受试者和方法

在作者所在机构,接受全甲状腺切除术或完成甲状腺切除术的患者采用当日出院算法,该算法将麻醉后护理单元的快速 PTH 作为主要出院标准。PTH>30pg/mL 的患者有资格无需补充即当日出院,PTH 在 20-30pg/mL 之间的患者有资格出院但接受钙补充,PTH<20pg/mL 的患者接受钙和维生素 D 补充过夜(23 小时)。

结果

180 例患者(平均年龄 48.9 岁;83.3%为女性)接受了全甲状腺切除术(77.2%)或完成甲状腺切除术(22.7%),并进行了淋巴结清扫或不进行淋巴结清扫。42%的手术采用微创视频辅助(MIVA)技术。76%(137/180)的患者 PTH>20pg/mL,符合 PTH 出院标准。69%(95/137)符合出院条件的患者当天出院(总出院人数的 53.1%)。10%的出院患者因引流管放置而入院。在门诊手术的 95 例患者中,无患者在术后出现低钙血症症状而需要住院、就诊或电话咨询。所有 180 例患者在术后第 7 天和第 30 天就诊时血钙正常。术后第 30 天无患者甲状旁腺功能减退。完成甲状腺切除术与全甲状腺切除术之间(11.1%比 22.2%,P=.28)或 MIVA 与标准技术之间(P=.37)术后甲状旁腺功能减退无显著差异。

结论

基于 PTH 的出院算法可安全促进门诊全甲状腺切除术或完成甲状腺切除术,门诊低钙血症的临床显著风险极小。

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