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年轻生物体甲状腺血管形成的相关方面(基于形态学和放射性同位素的研究)

Aspects of the thyroid gland vascularization in young organisms (a morphological and radioisotope-based study).

作者信息

Rottenberg N, Rottenberg F, Matusz P

机构信息

Anatomy Laboratory, Medical Institute, Timişoara, Romania.

出版信息

Morphol Embryol (Bucur). 1990 Jan-Mar;36(1):3-8.

PMID:2149409
Abstract

The thyroid gland vascularization has been studied on 58 pieces belonging to young organisms (human and animal) by means of both morphometric methods (macro- and microscopic) and injection of radioisotopes (86Rb). The statistical-mathematical study of the dimensional values characterizing the thyroid vascular branch at different levels assumed for study allowed to determine the thyroid central area as the best vascularized of the thyroid parenchyma. Estimating the specific activity and the absorption constant value of the 86Rb in the vascular wall and the glandular parenchyma, the radioisotope-based study attests the data obtained morphologically. By the simultaneous injection of 86Rb into strychnine, the pharmacodynamic study shows a more prominent reduction of the 86Rb absorption constant value in the distal area of the gland as compared to its central one and the blank batch.

摘要

通过形态计量学方法(宏观和微观)以及放射性同位素(86Rb)注射,对58份来自年轻生物体(人类和动物)的样本进行了甲状腺血管形成的研究。对所研究的甲状腺血管分支在不同水平的尺寸值进行统计数学研究,确定甲状腺中央区域是甲状腺实质中血管化程度最好的区域。通过估计86Rb在血管壁和腺实质中的比活度和吸收常数,基于放射性同位素的研究证实了形态学获得的数据。通过将86Rb与士的宁同时注射,药效学研究表明,与甲状腺中央区域和空白组相比,甲状腺远端区域86Rb吸收常数的降低更为显著。

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