精神分裂症患者的神经软体征、认知功能障碍和脑室脑比率。
Neurological soft signs, cognitive dysfunction and ventricular brain ration in schizophrenics.
机构信息
M.D., Professor, Department of Psychiatry, K.G. Medical College, Lucknow.
出版信息
Indian J Psychiatry. 1998 Apr;40(2):180-5.
An association between cognitive dysfunction, neurological soft signs, enlarged brain ventricles and widened cortical sulci has been reported in schizophrenia. The present work aimed to study the relevance of positive and negative dichotomy with relation to neuropsychological performance of the schizophrenic patients, and the presence of neurological soft signs. In 23 schizophrenics patients diagnosed according to DSM-III-R of which 14 were of positive subtype and 9 were of negative subtype. At least one neurological soft sign was present in all the patients. The positive group had higher WMS and IQ scores and lower BGT scores than the negative group. Negative, correlation was seen for WMS and BGT scores with Ventricular Brain Ratio (VBR), and the soft signs showed positive correlation in the positive subtype only.
已有研究表明，精神分裂症患者的认知功能障碍、神经软体征、脑室扩大和脑沟增宽之间存在关联。本研究旨在探讨阳性和阴性症状分类与精神分裂症患者神经认知表现及神经软体征之间的相关性。研究对象为 23 名符合 DSM-III-R 诊断标准的精神分裂症患者，其中 14 名患者为阳性亚型，9 名患者为阴性亚型。所有患者均至少存在一种神经软体征。阳性组的 WMS 和 IQ 评分高于阴性组，BGT 评分低于阴性组。WMS 和 BGT 评分与脑室脑比率（VBR）呈负相关，且仅在阳性亚型中，神经软体征与这两个评分呈正相关。
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