Great Lakes WATER Institute, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America.
PLoS One. 2011 Apr 11;6(4):e15274. doi: 10.1371/journal.pone.0015274.
We study the motility behavior of the unicellular protozoan Paramecium tetraurelia in a microfluidic device that can be prepared with a landscape of attracting or repelling chemicals. We investigate the spatial distribution of the positions of the individuals at different time points with methods from spatial statistics and Poisson random point fields. This makes quantitative the informal notion of "uniform distribution" (or lack thereof). Our device is characterized by the absence of large systematic biases due to gravitation and fluid flow. It has the potential to be applied to the study of other aquatic chemosensitive organisms as well. This may result in better diagnostic devices for environmental pollutants.
我们在一种微流控装置中研究单细胞原生动物四膜虫的运动行为,这种装置可以用有吸引力或排斥力的化学物质景观来制备。我们使用空间统计和泊松随机点场的方法来研究不同时间点个体位置的空间分布。这使得“均匀分布”(或缺乏分布)的非形式概念变得定量。我们的设备的特点是不存在由于重力和流体流动引起的大的系统偏差。它有可能应用于其他水生化学敏感生物的研究。这可能会导致更好的环境污染物诊断设备。