一名有流产史且育有一名唐氏综合征患儿的女性存在（14；21）（q11；q22）易位。
Translocation (14;21)(q11;q22) in a woman with history of abortions and a child with Down's syndrome.
作者信息
Sudha T, Gopinath P M
机构信息
Department of Genetics, University of Madras, India.
出版信息
Ann Genet. 1990;33(3):162-4.
PMID:2149630
Abstract
A translocation (14;21)(q11;q22) was observed in a woman with history of abortions and in her child with Down's syndrome. This appears to be the first report of such a translocation with no centric fusion between the acrocentric chromosomes leading to a count of 45 chromosomes in the carrier and giving birth to a Down's syndrome child.
摘要
在一位有流产史的女性及其患有唐氏综合征的孩子身上观察到了一种(14;21)(q11;q22)易位。这似乎是此类易位的首例报告，即近端着丝粒染色体之间没有着丝粒融合，导致携带者有45条染色体，并生育了一个唐氏综合征患儿。
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