真菌交配信息素：编排求偶游戏。
Fungal mating pheromones: choreographing the dating game.
机构信息
Graduate Program in Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, RI 02912, United States.
出版信息
Fungal Genet Biol. 2011 Jul;48(7):668-76. doi: 10.1016/j.fgb.2011.04.001. Epub 2011 Apr 8.
Abstract
Pheromones are ubiquitous from bacteria to mammals - a testament to their importance in regulating inter-cellular communication. In fungal species, they play a critical role in choreographing interactions between mating partners during the program of sexual reproduction. Here, we describe how fungal pheromones are synthesized, their interactions with G protein-coupled receptors, and the signals propagated by this interaction, using Saccharomyces cerevisiae as a reference point. Divergence from this model system is compared amongst the ascomycetes and basidiomycetes, which reveals the wealth of information that has been gleaned from studying pheromone-driven processes across a wide spectrum of the fungal kingdom.
摘要
信息素无处不在，从细菌到哺乳动物——这证明了它们在调节细胞间通讯方面的重要性。在真菌物种中，它们在性生殖过程中协调交配伴侣之间的相互作用中起着关键作用。在这里，我们描述了真菌信息素的合成方式、它们与 G 蛋白偶联受体的相互作用以及这种相互作用所传播的信号，以酿酒酵母作为参考点。与这个模型系统的差异在子囊菌和担子菌中进行了比较，这揭示了从研究广泛的真菌王国中信息素驱动的过程中获得的丰富信息。
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