Benito-León Julián, Louis Elan D
Department of Neurology, University Hospital "12 de Octubre" and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Handb Clin Neurol. 2011;100:449-56. doi: 10.1016/B978-0-444-52014-2.00034-3.
Essential tremor (ET) is one of the most common neurological disorders among adults. For many years, ET was viewed as a benign monosymptomatic condition, characterized by a kinetic arm tremor, yet over the last 10 years, a growing body of evidence suggests that this disorder is a progressive condition that is heterogeneous. Tremor may have a negative impact on health-related quality of life in some patients. Pharmacotherapy is initiated when the tremor interferes with the patient's ability to perform daily activities or when the tremor becomes embarrassing or affects health-related quality of life. For severe tremor, deep-brain stimulation of the thalamus may improve function.
特发性震颤（ET）是成年人中最常见的神经系统疾病之一。多年来，ET被视为一种良性单症状疾病，其特征为上肢运动性震颤，但在过去10年中，越来越多的证据表明，这种疾病是一种进行性且异质性的疾病。震颤可能会对一些患者与健康相关的生活质量产生负面影响。当震颤干扰患者进行日常活动的能力，或者震颤变得令人难堪或影响与健康相关的生活质量时，就会开始药物治疗。对于严重震颤，丘脑深部脑刺激可能会改善功能。
