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基于 V/Q 扫描的算法是否正确用于诊断急性肺栓塞?一项日常实践调查。

Is a V/Q scan based algorithm correctly used to diagnose acute pulmonary embolism? A daily practice survey.

机构信息

Department of General Internal Medicine, Section of Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.

出版信息

Thromb Res. 2011 Sep;128(3):221-6. doi: 10.1016/j.thromres.2011.03.019. Epub 2011 Apr 14.

DOI:10.1016/j.thromres.2011.03.019
PMID:21496884
Abstract

INTRODUCTION

Diagnostic flow-charts for pulmonary embolism (PE) are widely implemented in the management of PE. A major drawback of a diagnostic PE algorithm is the use of several consecutive tests, which may be challenging in daily clinical practice.

MATERIALS AND METHODS

Evaluation whether the use of an algorithm, starting with a ventilation/perfusion (V/Q) scan after a normal chest X-ray, is correctly used in daily clinical practice for diagnosing acute PE. Consecutive V/Q scans of patients with suspected acute PE were assessed to evaluate the use of the predefined diagnostic algorithm.

RESULTS

A chest X-ray had been performed in 101 of the 130 patients who underwent V/Q scanning; 89 patients had a normal chest X-ray. The V/Q scan was normal in 77/130 patients (59%), 30/130 patients (23%) had a non-high probability and 23/130 patients (18%) a high probability for PE. Only 3 of the 30 patients with a non-high V/Q scan (10%) underwent a computed tomographic pulmonary angiography (CTPA) scan, in contrast to the algorithm that required a CTPA scan in every patient with a non-high V/Q scan. Overall, the diagnostic strategy, starting with a V/Q scan as the baseline diagnostic tool with a prior chest X-ray, was appropriately followed in only 75/101 patients (74%).

CONCLUSIONS

A complex diagnostic algorithm for diagnosing PE is often not followed properly. This improper use of an algorithm could lead to a potential delay of establishing or excluding PE, a delay of therapy and/or unnecessary treatment. More simple algorithms could resolve this diagnostic management dilemma.

摘要

简介

肺栓塞(PE)的诊断流程图广泛应用于 PE 的管理中。诊断 PE 算法的一个主要缺点是使用了多个连续的测试,这在日常临床实践中可能具有挑战性。

材料与方法

评估在诊断急性 PE 时,从正常胸部 X 射线后开始进行通气/灌注(V/Q)扫描的算法是否在日常临床实践中得到正确使用。评估怀疑患有急性 PE 的患者连续的 V/Q 扫描,以评估预定义诊断算法的使用情况。

结果

在进行 V/Q 扫描的 130 名患者中,有 101 名患者进行了胸部 X 射线检查;89 名患者的胸部 X 射线正常。130 名患者中有 77/130 名(59%)V/Q 扫描正常,30/130 名(23%)为非高概率,23/130 名(18%)为高概率。只有 30 名非高 V/Q 扫描患者中的 3 名(10%)接受了计算机断层肺动脉造影(CTPA)扫描,而算法要求对每例非高 V/Q 扫描患者进行 CTPA 扫描。总体而言,只有 75/101 名(74%)患者正确遵循了以 V/Q 扫描作为基线诊断工具并进行胸部 X 射线检查的诊断策略。

结论

诊断 PE 的复杂诊断算法通常未得到正确遵循。这种算法的不当使用可能导致潜在的 PE 确诊或排除延迟、治疗延迟和/或不必要的治疗。更简单的算法可以解决这种诊断管理困境。

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