Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Department of Otolaryngology-Head and Neck Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
J Am Acad Dermatol. 2011 Aug;65(2):377-388. doi: 10.1016/j.jaad.2010.03.027. Epub 2011 Apr 15.
Nonmelanoma skin cancers can be treated by various modalities, including electrodessication and curettage, excisional techniques, and radiation. In selected cases, radiation may be preferable to surgery. When radiation is an option, brachytherapy, a form of radiation therapy that places the radiation source close to the area to be treated, may have advantages relative to conventional external beam radiation in particular patients. After brachytherapy, recurrence rates for nonmelanoma skin cancers are low, especially for small, superficial lesions, with good to excellent functional and cosmetic results. This article reviews the indications, efficacy, and adverse effects of brachytherapy in the treatment of nonmelanoma skin cancers.
非黑色素瘤皮肤癌可以通过多种方式治疗,包括电干燥和刮除术、切除术技术和放射治疗。在某些情况下,放射治疗可能优于手术。当放射治疗是一种选择时,近距离放射治疗(一种将放射源置于要治疗的区域附近的放射治疗形式)可能相对于传统的外照射放射治疗在某些特定患者中具有优势。近距离放射治疗后,非黑色素瘤皮肤癌的复发率较低,尤其是对于小的、表浅的病变,具有良好至极好的功能和美容效果。本文综述了近距离放射治疗治疗非黑色素瘤皮肤癌的适应证、疗效和不良反应。