Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Ludwig-Maximilians-University, Nussbaumstrasse 5a, D-80336 Munich, Germany.
J Affect Disord. 2011 Sep;133(1-2):69-75. doi: 10.1016/j.jad.2011.03.026. Epub 2011 Apr 16.
Depression in adolescents is often hard to detect. In many cases paediatricians are the first point of contact. In order to increase recognition rates, screening instruments may be a helpful support for health care professionals. However, there is a lack of valid and economical screening instruments for primary care patients. Thus, the aim of the study was the development of the new Depression Screener for Teenagers (DesTeen) and its validation in a paediatric sample.
326 patients between 13 and 16 years old completed the DesTeen and a diagnostic interview, serving as gold standard. Prevalence rate for any depressive disorder (minor depression, major depression and dysthymia) was 12.6%. Psychometric properties were calculated. For validity measures, the area under the receiver operating characteristic curves (AUC) for any depressive disorder and the diagnostic subgroups was computed.
DesTeen showed a high reliability (Cronbach's α=.87) and a high validity (AUC=.91). For the diagnostic subgroups AUC values did not significantly differ from overall accuracy of any depressive disorder (major depression: AUC=.95, p=.179; dysthymia: AUC=.88, p=.605; minor depression: AUC=.87, p=.327). The optimal cut-off point for any depressive disorder according to the Youden-Index yielded a sensitivity of .90 and a specificity of .80. An abbreviated 5-item version of DesTeen showed no loss in validity (AUC=.90, p=.695).
Overall, DesTeen can be regarded as a valid screening instrument for adolescent paediatric patients. For practical use, the 5-item version is even more promising. A replication of these results is essential.
青少年抑郁症往往难以察觉。在许多情况下,儿科医生是第一个接触点。为了提高识别率,筛查工具可能是医疗保健专业人员的有益支持。然而,对于初级保健患者,缺乏有效的经济筛查工具。因此,研究的目的是开发新的青少年抑郁筛查工具(DesTeen),并在儿科样本中验证其有效性。
326 名 13 至 16 岁的患者完成了 DesTeen 和诊断访谈,作为金标准。任何抑郁障碍(轻度抑郁、重度抑郁和恶劣心境)的患病率为 12.6%。计算了心理测量特性。对于有效性测量,计算了任何抑郁障碍和诊断亚组的接收者操作特征曲线(AUC)下的面积。
DesTeen 显示出较高的可靠性(Cronbach's α=.87)和较高的有效性(AUC=.91)。对于诊断亚组,AUC 值与任何抑郁障碍的总体准确性没有显著差异(重度抑郁:AUC=.95,p=.179;恶劣心境:AUC=.88,p=.605;轻度抑郁:AUC=.87,p=.327)。根据 Youden-Index 得出的任何抑郁障碍的最佳截断点的灵敏度为.90,特异性为.80。DesTeen 的简化 5 项版本没有丧失有效性(AUC=.90,p=.695)。
总体而言,DesTeen 可被视为青少年儿科患者的有效筛查工具。对于实际应用,5 项版本更有前途。复制这些结果至关重要。