Marañón Eugenio, Omonte John, Alvarez María Loreto, Serra José Antonio
Servicio de Geriatría, Hospital General Universitario Gregorio Marañón, Madrid, España.
Rev Esp Geriatr Gerontol. 2011 May-Jun;46(3):151-62. doi: 10.1016/j.regg.2011.01.005. Epub 2011 Apr 16.
Osteoporosis and the subsequent fractures caused by this are a source of morbidity and mortality in the elderly population. It is also often the start of the cascade that culminates in frailty and dependence. Vitamin D has a direct relationship with the appearance of osteoporosis and with the risk of fractures. Receptors of this vitamin have also recently been described in other organs and systems of the body that are associated with muscle strength, cancer and overall mortality. Deficiency of this vitamin in the elderly population in Spain is very prevalent, both in the community and the hospitalised elderly. The diagnosis and treatment are straightforward and cheap. Its efficacy in the prevention of osteoporosis and in the appearance of fractures is perfectly demonstrated. In this review, we will look at the physiology and actions of this vitamin, as well as the principal studies that have demonstrated its effectiveness in the elderly population.
骨质疏松症及其引发的骨折是老年人群发病和死亡的一个原因。它通常也是导致身体虚弱和依赖的一系列连锁反应的开端。维生素D与骨质疏松症的出现以及骨折风险有着直接关系。最近在身体其他与肌肉力量、癌症和总体死亡率相关的器官和系统中也发现了这种维生素的受体。在西班牙老年人群中，这种维生素缺乏在社区老年人和住院老年人中都非常普遍。其诊断和治疗简单且成本低廉。它在预防骨质疏松症和骨折发生方面的功效已得到充分证明。在这篇综述中，我们将探讨这种维生素的生理功能和作用，以及那些证明其在老年人群中有效性的主要研究。
