小鼠实验性2型单纯疱疹感染的细胞学评估
Cytologic evaluation of experimental type 2 herpes simplex infection in mice.
作者信息
Williams D R, Whitney J E, Harding M, Bodfish K, Skinner G R
出版信息
Acta Cytol. 1978 Sep-Oct;22(5):410-6.
The nature and frequency of cytopathologic changes in female mice genitally infected with type 2 herpes simplex virus have been investigated. The extent of virus infection in an individual mouse was assessed by a system of "plus scoring". Exfoliative cytology clearly provided a reliable evaluation of the extent of virus infection and a reliable prognostic index of mouse mortality. A composite index combining both cytologic and virologic information ('vircyt' value) was derived and shown to provide a convenient and precise prognostic index of mouse mortality.
对经生殖器感染2型单纯疱疹病毒的雌性小鼠的细胞病理学变化的性质和频率进行了研究。通过“加分评分”系统评估单个小鼠的病毒感染程度。脱落细胞学检查清楚地提供了对病毒感染程度的可靠评估以及小鼠死亡率的可靠预后指标。得出了一个结合细胞学和病毒学信息的综合指数（“病毒细胞”值），并证明它能提供一个方便且精确的小鼠死亡率预后指标。
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