Bredgaard Rikke, Lock-Andersen Jørgen
Department of Plastic Surgery, Roskilde County Hospital, Roskilde, Denmark.
J Plast Surg Hand Surg. 2011 Apr;45(2):113-6. doi: 10.3109/2000656X.2010.550472.
Late recurrence 10 years or more after treatment for localised cutaneous malignant melanoma is unusual. We present three cases with recurrences of cutaneous melanoma after 20 years or more. Two patients presented with a nodal recurrence and one patient with systemic disease. According to published reports, risk factors for late recurrence cannot be defined. Prognosis depends on the site of recurrence with short survival after distant metastases and longer survival after local and regional recurrence. Long-term follow up is advocated.
局部皮肤恶性黑色素瘤治疗后10年或更长时间出现晚期复发的情况并不常见。我们报告了3例皮肤黑色素瘤在20年或更长时间后复发的病例。2例患者出现淋巴结复发，1例患者出现全身疾病。根据已发表的报告，无法确定晚期复发的危险因素。预后取决于复发部位，远处转移后生存期短，局部和区域复发后生存期长。提倡进行长期随访。
