Departments of Pedodontics Endodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
Dent Traumatol. 2011 Jun;27(3):174-8. doi: 10.1111/j.1600-9657.2011.00995.x. Epub 2011 Apr 19.
Abstract - Background: The aim of this in vitro study was to assess the long-term fracture resistance of human immature permanent teeth filled with BioAggregate (BA), mineral trioxide aggregate (MTA) and calcium hydroxide (CH).
The study consisted of single rooted premolar teeth with immature root formation extracted for orthodontic reasons. A total of 28 immature premolars with average root length of 10.7 mm and apical diameter of 3 mm were included in the study. The pulps were extirpated and the canals were prepared using an apical approach. The teeth were randomly assigned to four groups: Group I: DiaRoot(®) BA (DiaDent, Burnaby, BC, Canada), Group II: Angelus MTA (MTA-A; Angelus, Londrina, Brazil), Group III: ProRoot(®) MTA (MTA-PR; Dentsply, Tulsa, OK, USA), Group IV: CH (Sultan Chemists Inc., Englewood, NJ, USA). The teeth were placed in saline solution at 4°C for 1 year. The root of each tooth was then embedded in an acrylic resin block. All specimens were loaded at a crosshead speed of 1 mm min(-1) in an Instron testing machine and the peak loads up to fracture were recorded. Data were analysed statistically by Kruskal-Wallis and Mann-Whitney U-tests.
Mean (±SD) failure loads (MPa) were: 37.69 ± 14.43 for BA group, 32.94 ± 8.15 for MTA-A group, 28.74 ± 9.49 for MTA-PR group and 23.18 ± 8.48 for CH group. The BA group exhibited the highest fracture resistance and the CH group showed the lowest resistance to fracture. Significant differences (P < 0.05) in fracture resistance were found between the DiaRoot-BA and CH groups, and also between the MTA-A and CH groups.
Within the limitations of this study, data suggest that DiaRoot-BA-filled immature teeth demonstrate higher fracture resistance than other groups at 1 year. Considering the long-term risk of cervical root fracture associated with immature teeth, the use of DiaRoot-BA as a root canal filling material appears to be the most advantageous of the materials tested.
本体外研究旨在评估用生物骨料（BA）、三氧化矿物聚合体（MTA）和氢氧化钙（CH）填充的人未成熟恒牙的长期抗折能力。
本研究纳入因正畸原因拔除的单根前磨牙。共纳入 28 颗具有平均根长 10.7mm 和根尖直径 3mm 的未成熟前磨牙。牙髓被切除，使用根尖入路预备根管。牙齿被随机分配到四组：I 组：DiaRoot®BA（DiaDent，不列颠哥伦比亚省本拿比）；II 组：Angelus MTA（MTA-A；Angelus，巴西隆德里纳）；III 组：ProRoot®MTA（MTA-PR；Dentsply，俄克拉荷马州塔尔萨）；IV 组：CH（Sultan Chemists Inc.，新泽西州恩格尔伍德）。将牙齿置于 4°C 的盐水中 1 年。然后将每个牙齿的根尖嵌入丙烯酸树脂块中。所有标本均在 Instron 试验机上以 1mm/min 的十字头速度加载，并记录至断裂的峰值载荷。数据通过 Kruskal-Wallis 和 Mann-Whitney U 检验进行统计学分析。
平均（±SD）断裂载荷（MPa）为：BA 组 37.69±14.43，MTA-A 组 32.94±8.15，MTA-PR 组 28.74±9.49，CH 组 23.18±8.48。BA 组表现出最高的抗断裂能力，而 CH 组表现出最低的抗断裂能力。DiaRoot-BA 与 CH 组以及 MTA-A 与 CH 组之间的抗断裂能力存在显著差异（P<0.05）。
在本研究的限制范围内，数据表明，在 1 年时，用 DiaRoot-BA 填充的未成熟牙齿表现出比其他组更高的抗断裂能力。考虑到与未成熟牙齿相关的颈根骨折的长期风险，DiaRoot-BA 作为根管填充材料的使用似乎是最有利的。
